THE SYNTHESIS OF SUBSTITUTED ARYL DIAZIRINES - A BIFUNCTIONAL REAGENT SUITABLE FOR APPLICATION TO PHOTOAFFINITY-LABELING STUDIES

被引：15

作者：

BALDWIN, JE

JESUDASON, CD

MOLONEY, MG

MORGAN, DR

PRATT, AJ

机构：

[1] The University of Oxford, The Dyson Perrins Laboratory, Oxford, OX1 3QY, South Parks Road

来源：

TETRAHEDRON | 1991年 / 47卷 / 29期

关键词：

PHOTOAFFINITY; DIAZIRINE; BIFUNCTIONAL; CARBENE; PENICILLIN;

D O I：

10.1016/S0040-4020(01)80991-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 1,3,5-trisubstituted aryl diazirine(2) has been synthesised as a photoaffinity probe and has been elaborated to a reagent suitable for application to studies of penicillin and cephalosporin biosynthetic enzymes.

引用

页码：5603 / 5614

页数：12

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