MECHANISM OF BLEOMYCIN - EVIDENCE FOR 4'-KETONE FORMATION IN POLY(DA-DU) ASSOCIATED EXCLUSIVELY WITH FREE BASE RELEASE

被引：53

作者：

WU, JC

STUBBE, J

KOZARICH, JW

机构：

[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

[2] YALE UNIV,SCH MED,CTR THORAC SURG,DEV THERAPEUT PROGRAM,NEW HAVEN,CT 06510

[3] UNIV WISCONSIN,COLL AGR & LIFE SCI,DEPT BIOCHEM,MADISON,WI 53706

来源：

BIOCHEMISTRY | 1985年 / 24卷 / 26期

关键词：

D O I：

10.1021/bi00347a010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7569 / 7573

页数：5

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WU JC, 1983, J BIOL CHEM, V258, P4694

[10] MECHANISM OF BLEOMYCIN - EVIDENCE FOR A RATE-DETERMINING 4'-HYDROGEN ABSTRACTION FROM POLY(DA-DU) ASSOCIATED WITH THE FORMATION OF BOTH FREE BASE AND BASE PROPENYL [J].

WU, JC ;

KOZARICH, JW ;

STUBBE, J .

BIOCHEMISTRY, 1985, 24 (26) :7562-7568

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