NUCLEAR OVERHAUSER DATA AND STEREOCHEMICAL CONSIDERATIONS SUGGEST THAT NETROPSIN BINDS SYMMETRICALLY WITHIN THE MINOR GROOVE OF POLY(DA).POLY(DT), FORMING HYDROGEN-BONDS WITH BOTH STRANDS OF THE DOUBLE HELIX

被引：21
作者：
DICKERSON, RE
KOPKA, ML
机构：
来源：
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 1985年 / 3卷 / 03期
关键词：
D O I：
10.1080/07391102.1985.10508431
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
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页码：423 / 431
页数：9
相关论文
共 8 条
[1]   HETERONOMOUS DNA [J].
ARNOTT, S ;
CHANDRASEKARAN, R ;
HALL, IH ;
PUIGJANER, LC .
NUCLEIC ACIDS RESEARCH, 1983, 11 (12) :4141-4155
[2]  
FRATINI AV, 1982, J BIOL CHEM, V257, P4686
[3]   BINDING OF AN ANTITUMOR DRUG TO DNA NETROPSIN AND C-G-C-G-A-A-T-T-BRC-G-C-G [J].
KOPKA, ML ;
YOON, C ;
GOODSELL, D ;
PJURA, P ;
DICKERSON, RE .
JOURNAL OF MOLECULAR BIOLOGY, 1985, 183 (04) :553-563
[4]   THE MOLECULAR-ORIGIN OF DNA DRUG SPECIFICITY IN NETROPSIN AND DISTAMYCIN [J].
KOPKA, ML ;
YOON, C ;
GOODSELL, D ;
PJURA, P ;
DICKERSON, RE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (05) :1376-1380
[5]   NETROPSIN.DG-DG-DA-DA-DT-DT-DC-DC COMPLEX - ANTIBIOTIC BINDING AT ADENINE-THYMINE BASE-PAIRS IN THE MINOR GROOVE OF THE SELF-COMPLEMENTARY OCTANUCLEOTIDE DUPLEX [J].
PATEL, DJ .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1979, 99 (02) :369-378
[6]   ANTIBIOTIC-DNA INTERACTIONS - INTERMOLECULAR NUCLEAR OVERHAUSER EFFECTS IN THE NETROPSIN-D (C-G-C-G-A-A-T-T-C-G-C-G) COMPLEX IN SOLUTION [J].
PATEL, DJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (21) :6424-6428
[7]   UNTENABILITY OF THE HETERONOMOUS DNA MODEL FOR POLY(DA).POLY(DT) IN SOLUTION - THIS DNA ADOPTS A RIGHT-HANDED B-DNA DUPLEX IN WHICH THE 2 STRANDS ARE CONFORMATIONALLY EQUIVALENT - A 500 MHZ NMR-STUDY USING ONE DIMENSIONAL NOE [J].
SARMA, MH ;
GUPTA, G ;
SARMA, RH .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1985, 2 (06) :1057-1084
[8]   NETROPSIN SPECIFICALLY RECOGNIZES ONE OF THE 2 CONFORMATIONALLY EQUIVALENT STRANDS OF POLY(DA).POLY(DT) - ONE DIMENSIONAL NMR-STUDY AT 500 MHZ INVOLVING NOE TRANSFER BETWEEN NETROPSIN AND DNA PROTONS [J].
SARMA, MH ;
GUPTA, G ;
SARMA, RH .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1985, 2 (06) :1085-1095
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