Rough mereology classifier vs. simple DNA microarray gene extraction methods

被引:3
|
作者
Artiemjew, Piotr [1 ]
机构
[1] Univ Warmia & Mazury, Dept Math & Comp Sci, Sloneczna 54, PL-10710 Olsztyn, Poland
关键词
rough mereology; granular computing; rough sets; DNA microarrays;
D O I
10.1504/IJDMMM.2014.063193
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
This work extends the author's contribution to the Second International Conference of Soft Computing and Pattern Recognition (SocPar 2010) held at the University of Cergy Pontoise in December 2010. The current version is dedicated to the topic of gene separation algorithms and our best classification method based on weighted voting, which was investigated recently by Polkowski and Artiemjew. The DNA microarrays are a popular tool, useful to the research of gene expression. The exemplary application is, among others, to differentiate healthy and ill tissues, distinguishing some organisms' features or to check changes in gene expression by means of some additional factors. The huge amount of information obtained from DNA microarrays in the range of tens of thousands of genes causes many difficulties. Many algorithms, especially brute force methods, cannot be applied for this reason, and due to the low number of training objects tend to overfit. In this paper, we present two simple gene extraction methods compared by means of our best weighted voting classifier. The results of research show the high effectiveness of our approach, and full comparability with the results of the recent DNA microarray data mining competition.
引用
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页码:110 / 126
页数:17
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