A multi-channel fully differential programmable integrated circuit for neural recording application

被引:3
|
作者
Gui Yun [1 ]
Zhang Xu [1 ]
Wang Yuan [1 ]
Liu Ming [1 ]
Pei Weihua [1 ]
Liang Kai [2 ]
Huang Suibiao [2 ]
Li Bin [2 ]
Chen Hongda [1 ]
机构
[1] Chinese Acad Sci, Inst Semicond, State Key Lab Integrated Optoelect, Beijing 100083, Peoples R China
[2] South China Univ Technol, Sch Elect & Informat Engn, Guangzhou 510000, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
neural recording system; multi-channel; preamplifier; programmable gain amplifier; switch capacitor filter; time-division multiplexer; SAR ADC; in vivo recording;
D O I
10.1088/1674-4926/34/10/105009
中图分类号
O469 [凝聚态物理学];
学科分类号
070205 ;
摘要
A multi-channel, fully differential programmable chip for neural recording application is presented. The integrated circuit incorporates eight neural recording amplifiers with tunable bandwidth and gain, eight 4th-order Bessel switch capacitor filters, an 8-to-1 analog time-division multiplexer, a fully differential successive approximation register analog-to-digital converter (SAR ADC), and a serial peripheral interface for communication. The neural recording amplifier presents a programmable gain from 53 dB to 68 dB, a tunable low cut-off frequency from 0.1 Hz to 300 Hz, and 3.77 mu V-rms input-referred noise over a 5 kHz bandwidth. The SAR ADC digitizes signals at maximum sampling rate of 20 kS/s per channel and achieves an ENOB of 7.4. The integrated circuit is designed and fabricated in 0.18-mu m CMOS mix-signal process. We successfully performed a multi-channel in-vivo recording experiment from a rat cortex using the neural recording chip.
引用
收藏
页数:8
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