Mechanochemical Preparation and Properties of Water-Soluble Intermolecular Complexes of Polysaccharides and beta-Cyclodextrin with Pharmaceutical Substances

被引：0
|
作者：
Dushkin, A. V. [1 ]
Meteleva, E. S. [1 ]
Tolstikova, T. G. [2 ]
Khvostov, M. V. [2 ]
Tolstikov, G. A. [2 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Inst Solid State Chem & Mechanochem, Ul Kutateladze 18, Novosibirsk 6300128, Russia
[2] Russian Acad Sci, Siberian Branch, Vorozhtsov Novosibirsk Inst Organ Chem, Novosibirsk 630090, Russia
来源：
CHEMISTRY FOR SUSTAINABLE DEVELOPMENT | 2010年 / 18卷 / 06期
关键词：
water-soluble supramolecular complexes; arabinogalactan; beta-cyclodextrin; polysaccharides; pharmacological properties; mechanical destruction; low-soluble pharmaceutical substances;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Comparative investigation of obtaining conditions and the "stability" of water-soluble intermolecular complexes of low-soluble pharmaceutical substances and different polysaccharides with beta-cyclodextrin was carried out. Substantial improvement of the pharmacological characteristics of resulting complexes in comparison with initial pharmaceutical substances was demonstrated.
引用
收藏
页码：631 / 640
页数：10
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