A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain

被引：1

作者：

Tabuchi, Yukiko ^{[1
]}

Yasuda, Tetsuyuki ^{[1
]}

Kaneto, Hideaki ^{[1
]}

Kitamura, Tetsuhiro ^{[1
]}

Kozawa, Junji ^{[1
]}

Otsuki, Michio ^{[1
]}

Imagawa, Akihisa ^{[1
]}

Nakae, Aya ^{[2
]}

Matsuda, Youichi ^{[2
]}

Uematsu, Hironobu ^{[3
]}

Mashimo, Takashi ^{[2
]}

Shibata, Masahiko ^{[4
]}

Shimomura, Iichiro ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Med, Dept Metab Med, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Grad Sch Med, Anesthesiol & Intens Care, Suita, Osaka 5650871, Japan

[3] Osaka Prefectural Med Ctr Resp & Allerg Dis, Dept Anesthesiol, Habikino 5838588, Japan

[4] Osaka Univ, Grad Sch Med, Pain Med, Suita, Osaka 5650871, Japan

来源：

CASE REPORTS IN MEDICINE | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/740603

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment.

引用

页数：5

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