LEISHMANIA-DONOVANI - ISOLATION OF A CONCANAVALIN-A SPECIFIC ANTIGEN AND ITS EVALUATION FOR SERODIAGNOSIS OF VISCERAL LEISHMANIASIS

被引：3
|
作者：
BHATTACHARYA, M
BANERJEE, N
GHOSH, DK
机构：
[1] INDIAN INST EXPTL MED,DEPT IMMUNOCHEM,LEISHMANIA GRP,4 RAJA SC MULLICK RD,CALCUTTA 700032,W BENGAL,INDIA
[2] INDIAN INST EXPTL MED,DEPT ORGAN CHEM CARBOHYDRATE,CALCUTTA 700032,W BENGAL,INDIA
来源：
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY | 1992年 / 86卷 / 04期
关键词：
D O I：
10.1080/00034983.1992.11812676
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
A glycoconjugate antigen of 27-39 kDa was isolated from a cell-free extract of Leishmania donovani by affinity chromatography using a Concanavalin-A sepharose-4B column and eluted with 0.5 M α-methylmannoside. The antigen was recognized specifically by sera from kala-azar (visceral leishmaniasis) patients and did not react with sera from tuberculosis, leprosy or malaria patients. The antigen may therefore be useful in developing a serodiagnostic assay for visceral leishmaniasis.
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页码：341 / 345
页数：5
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