PHYSICAL MAPPING OF 60DNA MARKERS IN THE P21.1-]Q21.3 REGION OF THE HUMAN X-CHROMOSOME

被引：93
|
作者：
LAFRENIERE, RG
BROWN, CJ
POWERS, VE
CARREL, L
DAVIES, KE
BARKER, DF
WILLARD, HF
机构：
[1] STANFORD UNIV,MED CTR,SCH MED,DEPT GENET,STANFORD,CA 94305
[2] JOHN RADCLIFFE HOSP,INST MOLEC MED,OXFORD OX3 9DU,ENGLAND
[3] UNIV UTAH,DEPT MED INFORMAT,SALT LAKE CITY,UT 84108
来源：
GENOMICS | 1991年 / 11卷 / 02期
关键词：
D O I：
10.1016/0888-7543(91)90143-3
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Using a panel of human/rodent somatic cell hybrids and human lymphoblast lines segregating 18 different human X-chromosome rearrangements and deletions, we have assigned 60 DNA markers to the physical map of the X chromosome from Xp21.1 to Xq21.3. Data from Southern blot hybridization and polymerase chain reaction (PCR) amplification assign these markers to 15 primary map intervals. This provides a basis for further long-range cloning and mapping of the pericentromeric region of the X chromosome. © 1991.
引用
收藏
页码：352 / 363
页数：12
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