AN EXPERIMENTAL OSTEOSARCOMA OF THE ATHYMIC NUDE RAT

被引：0
|
作者：
WITZEL, JG
PRESCHER, A
机构：
来源：
INVASION & METASTASIS | 1991年 / 11卷 / 02期
关键词：
EXPERIMENTAL TUMOR MODEL; NUDE RAT; OSTEOSARCOMA;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this report we describe an experimental osteogenic sarcoma that had been radiation-induced on Sprague-Dawleys by Delbruck in 1980. We transplanted it to 120 athymic nude rats achieving take rates of 100%. The tumor doubling time was 10.5 days. The osteosarcoma on athymic rats thus proliferated extraordinarily well compared to other known models. Pulmonary metastases were demonstrated in 100% of the examined animals. Pathological examinations revealed morphological similarities to human osteosarcoma and no signs of anaplasia.
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页码：110 / 115
页数：6
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