Resting heart rate in patients with ischemic heart disease in Saudi Arabia and Egypt

Aim: To assess the level of resting heart rate (RHR) in an outpatient population presenting with stable coronary artery disease (CAD) as well as to measure its association with current therapeutic management strategies for cardiovascular events. Materials and methods: A multi-center cross-sectional survey was carried out in Saudi Arabia and Egypt over a three month period (between January 2007 and April 2007). 2049 patients with CAD without clinical heart failure (HF) were included in this study through "cluster sampling''. RHR was measured by manual palpitation. Results: Mean age of CAD patients was 56.7 +/- 10.4 and the mean RHR was 78.9 +/- 13.9 b/m. 1686 patients (83.1%) were on b-blockers for whom the RHR was 78.5 +/- 14.0 b/m (95.5% had RHR >= 60 b/m, which is higher than recommended by the guidelines). 1094 (73.5%) of patients on beta-blockers were on a lower dose, probably to avoid the complications associated with such a class. Among those not on b-blockers (16.9%), RHR was 80.9 +/- 13.0 b/m. Moreover, 98 patients (4.8%) were on calcium channel blocker (diltiazem or verapamil) but not on beta-blockers, for whom the RHR was 80.9 +/- 12.0 b/m. Finally, 163 patients (8.0%) were on both beta-blockers and the calcium channel blocker, and their RHR was 79.0 +/- 14.4 b/m. Conclusion: Optimal target RHR has not been achieved in a significant number of screened patients. Achievements of such targets are known to decrease mortality and to improve survival. (C) 2011 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.