SUCCESSFUL CONTROL OF INTRACTABLE NAUSEA AND VOMITING REQUIRING COMBINED ONDANSETRON AND HALOPERIDOL IN A PATIENT WITH ADVANCED CANCER

被引：39
|
作者：
COLE, RM
ROBINSON, F
HARVEY, L
TRETHOWAN, K
MURDOCH, V
机构：
[1] Bulli Hospital, Bulli, NSW
来源：
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 1994年 / 9卷 / 01期
关键词：
ANTIEMETICS; MEDICAL ONCOLOGY; PALLIATIVE TREATMENT; TERMINAL CARE; HOSPICE;
D O I：
10.1016/0885-3924(94)90147-3
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
Chemically induced nausea and vomiting is a common symptom of advanced cancer effected through stimulation of dopamine (D2) or serotonin (5-HT3) receptors located in the chemoreceptor trigger zone (CTZ). These may be blocked by therapeutic doses of haloperidol and ondansetron, respectively. This case, reporting on a single patient acting as her own control, establishes that combined blockade of these receptors is sometimes required to relieve intractable nausea and vomiting. R also demonstrates the value of clinical review, audit of care, and quality assurance in the palliative care setting.
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收藏
页码：48 / 50
页数：3
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