SYNTHESIS OF SIALYL-TN ANTIGEN - REGIOSELECTIVE SIALYLATION OF A GALACTOSAMINE THREONINE CONJUGATE UNBLOCKED IN THE CARBOHYDRATE PORTION

被引：36
|
作者：
LIEBE, B [1 ]
KUNZ, H [1 ]
机构：
[1] UNIV MAINZ,INST ORGAN CHEM,D-55099 MAINZ,GERMANY
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 47期
关键词：
D O I：
10.1016/S0040-4039(00)78495-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Regioselective and stereocontrolled formation of the sialyl-Tn antigen conjugate 6 was achieved by reacting the NeuNAc-2-xanthate 2 with the GalNAc threonine acceptor 5 bearing three hydroxy groups. Complete deprotection afforded the sialyl-Tn antigen structure 11.
引用
收藏
页码：8777 / 8778
页数：2
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