SYNTHESIS OF (+/-)-HALIPANICINE, A MARINE SESQUITERPENE ISOTHIOCYANATE ISOLATED FROM AN OKINAWAN MARINE SPONGE HALICHONDRIA-PANICEA

被引：12
|
作者：
NAKAMURA, H
YE, B
MURAI, A
机构：
[1] Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo
来源：
TETRAHEDRON LETTERS | 1992年 / 33卷 / 52期
关键词：
HALIPANICINE; MARINE SESQUITERPENE ISOTHIOCYANATE; MARINE SPONGE; HALICHONDRIA-PANICEA;
D O I：
10.1016/S0040-4039(00)74733-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
(+/-)-Halipanicine, 4-isothiocyanato-1-cadinene, isolated from an Okinawan marine sponge Halichondria panacea was synthesized from (+/-)-cryptone in 21 steps in 7.7% total yield. The regio- and stereospecific synthesis esablished the relative stereochemistry of halipanicine.
引用
收藏
页码：8113 / 8116
页数：4
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