The Effect of Virgin Coconut Oil Loaded Solid Lipid Particles (VCO-SLPs) on Skin Hydration and Skin Elasticity

被引:0
|
作者
Noor, Norhayati Mohamed [1 ]
Abd Aziz, Azila [1 ]
Sarmidi, Mohamad Roji [1 ]
Aziz, Ramlan [1 ]
机构
[1] Univ Teknol Malaysia, Inst Bioprod Dev, Utm Johor Bahru 81310, Johor, Malaysia
来源
JURNAL TEKNOLOGI | 2013年 / 62卷 / 01期
关键词
Solid lipid particles; virgin coconut oil; ultrasonification; moisturizer;
D O I
暂无
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Virgin Coconut Oil is usually extracted from well matured and fresh coconut through specialized processes without damaging its natural nutrition. In this work, formulation, characterization and efficacy of VCO-SLPs have been studied. VCO-SLPs were prepared using ultrasonification of molten stearic acid and virgin coconut oil in an aqueous solution and particles with the size of 0.608 mu m have been obtained. 20% concentration of VCO-SLPs of 0.608 mu m particle size was added into the base lotion. Sensory study and skin evaluation study was conducted to compare the difference between lotion containing VCO-SLPs and lotion without VCO-SLPs. Moisturizing lotion incorporated with VCO- SLPs was found to increase skin hydration and skin elasticity by 24.8% and 2.60% respectively from day 0 to day 28. This shows that solid lipid particles has the potential to be utilized as a carrier for improved dermal delivery of VCO.
引用
收藏
页数:5
相关论文
共 12 条
  • [1] Empty nano and micro-structured lipid carriers of virgin coconut oil for skin moisturisation
    Noor, Norhayati Mohamed
    Khan, Abid Ali
    Hasham, Rosnani
    Talib, Ayesha
    Sarmidi, Mohamad Roji
    Aziz, Ramlan
    Aziz, Azila Abd
    IET NANOBIOTECHNOLOGY, 2016, 10 (04) : 195 - 199
  • [2] Effect of Virgin Coconut Oil Application on the Skin of Preterm Newborns: A Randomized Controlled Trial
    Konar, Mithun Chandra
    Islam, Kamirul
    Roy, Atanu
    Ghosh, Taraknath
    JOURNAL OF TROPICAL PEDIATRICS, 2020, 66 (02) : 129 - 135
  • [3] DEET-loaded solid lipid particles for skin delivery:: In vitro release and skin permeation characteristics in different vehicles
    Iscan, Y.
    Hekimoglu, S.
    Sargon, M. F.
    Hincal, A. A.
    JOURNAL OF MICROENCAPSULATION, 2006, 23 (03) : 315 - 327
  • [4] Effect of lipid-containing, positively charged nanoemulsions on skin hydration, elasticity and erythema - An in vivo study
    Yilmaz, E
    Borchert, HH
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2006, 307 (02) : 232 - 238
  • [5] Effect of Topical Application of Virgin Coconut Oil on Skin Components and Antioxidant Status during Dermal Wound Healing in Young Rats
    Nevin, K. G.
    Rajamohan, T.
    SKIN PHARMACOLOGY AND PHYSIOLOGY, 2010, 23 (06) : 290 - 297
  • [6] Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid compositions
    Chantaburanan, Thitirat
    Teeranachaideekul, Veerawat
    Jintapattanakit, Anchalee
    Chantasart, Doungdaw
    Junyaprasert, Varaporn Buraphacheep
    INTERNATIONAL JOURNAL OF PHARMACEUTICS-X, 2023, 6
  • [7] THE EFFECT OF DIETARY-LIPID ON SKIN TUMOR PROMOTION BY BENZOYL PEROXIDE - COMPARISON OF FISH, COCONUT AND CORN-OIL
    LOCNISKAR, M
    BELURY, MA
    CUMBERLAND, AG
    PATRICK, KE
    FISCHER, SM
    CARCINOGENESIS, 1991, 12 (06) : 1023 - 1028
  • [8] Development and Evaluation of Elaeagnus rhamnoides (L.) A. Nelson Oil-Loaded Nanostructured Lipid Carrier for Improved Skin Hydration
    Chaiyasut, Chaiyavat
    Sivamaruthi, Bhagavathi Sundaram
    Jungsinyatam, Patchareepon
    Tansrisook, Chawin
    Jinarat, Damrongsak
    Chaiyasut, Khontaros
    Peerajan, Sartjin
    Rungseevijitprapa, Wandee
    APPLIED SCIENCES-BASEL, 2022, 12 (16):
  • [9] The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial
    Padilla Evangelista, Mara Therese
    Abad-Casintahan, Flordeliz
    Lopez-Villafuerte, Lillian
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2014, 53 (01) : 100 - 108
  • [10] A retinyl palmitate-loaded solid lipid nanoparticle system: Effect of surface modification with dicetyl phosphate on skin permeation in vitro and anti-wrinkle effect in vivo
    Jeon, Ho Seong
    Seo, Jo Eun
    Kim, Min Soo
    Kang, Mean Hyung
    Oh, Dong Ho
    Jeon, Sang Ok
    Jeong, Seong Hoon
    Choi, Young Wook
    Lee, Sangkil
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2013, 452 (1-2) : 311 - 320