EFFICACY AND SAFETY OF OFLOXACIN PLUS PIPERACILLIN IN THE TREATMENT OF ASPIRATION PNEUMONIA

被引:0
|
作者
NEVIERE, R
HERENGT, F
MATHIEU, D
RENAUD, N
WATTEL, F
机构
来源
MEDECINE ET MALADIES INFECTIEUSES | 1993年 / 23卷
关键词
PNEUMONIA; ASPIRATION; ANTIBIOTIC;
D O I
10.1016/S0399-077X(05)80965-5
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Aspiration pneumonia is common and often serious lung disease. Prognosis could be improved by effective prevention, early diagnosis and appropriate drug regimens. Since anti-microbial therapy is the key stone of treatment, it has been an area of debate and controversy. We evaluate the efficacy and safety of intravenous ofloxacin plus piperacillin. Our bacteriologic results show frequent pluri micro-organism cultures in sputum and frequent isolation of staphylococci in culture specimens. Clinical and bacteriological results demonstrate that intravenous ofloxacin plus piperacillin is effective (success = 28/30) and safe (no side effects) for the treatment of aspiration pneumonia.
引用
收藏
页码:409 / 412
页数:4
相关论文
共 50 条
  • [1] EFFICACY AND SAFETY OF ORAL OFLOXACIN FOR TREATMENT OF PNEUMONIA
    CHIDIAC, C
    LEROY, O
    BEUSCART, C
    LECHEVALIER, B
    BEAUCAIRE, G
    MOUTON, Y
    REVIEWS OF INFECTIOUS DISEASES, 1989, 11 : S1223 - S1224
  • [2] TREATMENT OF ASPIRATION PNEUMONIA BY PIPERACILLIN
    DUCROIX, JP
    TONDRIAUX, A
    SMAIL, A
    LOBJOIE, E
    LAURANS, G
    BAILLET, J
    PATHOLOGIE BIOLOGIE, 1990, 38 (5BIS): : 530 - 532
  • [3] Efficacy, safety, and tolerance of piperacillin/tazobactam compared to co-amoxiclav plus an aminoglycoside in the treatment of severe pneumonia
    R. Speich
    E. Imhof
    M. Vogt
    M. Grossenbacher
    W. Zimmerli
    European Journal of Clinical Microbiology and Infectious Diseases, 1998, 17 : 313 - 317
  • [4] Efficacy, safety, and tolerance of piperacillin/tazobactam compared to co-amoxiclav plus an aminoglycoside in the treatment of severe pneumonia
    Speich, R
    Imhof, E
    Vogt, M
    Grossenbacher, M
    Zimmerli, W
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1998, 17 (05) : 313 - 317
  • [5] Comparative efficacy of sparfloxacin in comparison with amoxycillin plus ofloxacin in the treatment of community-acquired pneumonia
    Portier, H
    May, T
    Proust, A
    Tolstuchow, N
    Muir, JF
    Balmes, P
    Paganin
    Carles, P
    Blanchon, F
    Rochemaure, J
    Tonnel, AB
    Dumont, P
    Wallaert, C
    Ragnaud, JM
    BecqGiraudon, B
    Nouvet, G
    Weitzenblum, E
    Leng, B
    Gaillat, J
    Defouilloy, C
    Arnaud, A
    Herer, B
    Miech, G
    Modai, J
    Crepin, JL
    Bernard, P
    Cordier, JF
    Bart, F
    Clavier, J
    Stahl, JP
    Polu, JM
    Lacroix, S
    Jeannin, L
    Benoit, JP
    Balgaries, JL
    Barbieux, H
    Beytout, J
    Pariente, R
    Patey, O
    Raffi, F
    Tuchais, E
    Sergeant, YH
    Choutet, P
    Caillaux, D
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1996, 37 : 83 - 91
  • [6] Clinical efficacy and safety of moxifloxacin versus levofloxacin plus metronidazole for community-acquired pneumonia with aspiration factors
    Sun Tieying
    Sun Li
    Wang Rongmei
    Ren Xiaoping
    Sui Dong-jiang
    Pu Chun
    Ren Yajuan
    Liu Ying
    Yang Zhuo
    Li Fengzhi
    CHINESE MEDICAL JOURNAL, 2014, 127 (07) : 1201 - 1205
  • [7] Clinical efficacy and safety of moxifloxacin versus levofloxacin plus metronidazole for community-acquired pneumonia with aspiration factors
    Sun Tieying
    Sun Li
    Wang Rongmei
    Ren Xiaoping
    Sui Dong-jiang
    Pu Chun
    Ren Yajuan
    Liu Ying
    Yang Zhuo
    Li Fengzhi
    中华医学杂志(英文版), 2014, (07) : 1201 - 1205
  • [8] EFFICACY AND SAFETY OF LORACARBEF IN THE TREATMENT OF PNEUMONIA
    HYSLOP, DL
    AMERICAN JOURNAL OF MEDICINE, 1992, 92 : S65 - S69
  • [9] CLINICAL SAFETY AND EFFICACY OF OFLOXACIN
    MARONE, P
    CONCIA, E
    GROSSI, P
    MALFITANO, A
    PERVERSI, L
    CHEMIOTERAPIA, 1988, 7 (05): : 320 - 322
  • [10] Ceftriaxone versus tazobactam/piperacillin and carbapenems in the treatment of aspiration pneumonia: A propensity score matching analysis
    Asai, Nobuhiro
    Suematsu, Hiroyuki
    Ohashi, Wataru
    Shibata, Yuichi
    Sakanashi, Daisuke
    Kato, Hideo
    Shiota, Arufumi
    Watanabe, Hiroki
    Hagihara, Mao
    Koizumi, Yusuke
    Yamagishi, Yuka
    Mikamo, Hiroshige
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 2021, 27 (10) : 1465 - 1470