PHASE-II STUDY OF TENIPOSIDE IN ADENOCARCINOMA OF THE LUNG

被引：3

作者：

SORENSEN, JB ^{[1
]}

BACH, F ^{[1
]}

DOMBERNOWSKY, P ^{[1
]}

HANSEN, HH ^{[1
]}

机构：

[1] UNIV COPENHAGEN,HERLEV HOSP,DK-2730 HERLEV,DENMARK

来源：

CANCER CHEMOTHERAPY AND PHARMACOLOGY | 1991年 / 27卷 / 06期

关键词：

D O I：

10.1007/BF00685166

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A total of 26 evaluable patients with previously untreated, non-resectable adenocarcinoma of the lung were given 80 mg/m2 i.v. teniposide daily for 5 days every 3 weeks. Three partial responses (11%) were obtained that lasted for 12, 11 and 32 weeks, respectively. Leucopenia was the dose-limiting side effect, with WBC counts of < 2 x 10(9)/l being observed in 42% of patients, resulting in one septic death. At the dose and schedule used in the present study, teniposide showed only limited activity in adenocarcinoma of the lung.

引用

页码：487 / 489

页数：3

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