CHROMOSOMAL LOCALIZATION AND SEQUENCES OF THE MURINE BRN-3 FAMILY OF DEVELOPMENTAL CONTROL GENES

被引：38
|
作者：
THEIL, T
ZECHNER, U
KLETT, C
ADOLPH, S
MOROY, T
机构：
[1] UNIV MARBURG, INST MOLEK BIOL & TUMORFORSCH, D-35037 MARBURG, GERMANY
[2] UNIV ULM, KLIN GENET ABT, W-7900 ULM, GERMANY
来源：
CYTOGENETICS AND CELL GENETICS | 1994年 / 66卷 / 04期
关键词：
D O I：
10.1159/000133709
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The POU proteins BRN-3a, -3b and -3c are transcription factors encoded by separate genes that are differentially expressed during neural development. Comparison of genomic and cDNA sequences revealed similar exon/intron structures for Brn-3a and -3c genes, whereas the Brn-3b gene appeared to contain an intronless coding region. Fluorescence in situ hybridization experiments with mouse chromosomes showed that Brn-3a maps to mouse chromosome 14E1-3, Brn-3b to XF1-5 and Brn-3c to 18B3-E1.
引用
收藏
页码：267 / 271
页数：5
相关论文
共 50 条
  • [1] Role of the Brn-3 family of POU-domain genes in the development of the auditory/nestibular, somatosensory, and visual systems
    Xiang, M
    Gan, L
    Li, D
    Zhou, L
    Chen, ZY
    Wagner, D
    O'Malley, BW
    Klein, W
    Nathans, J
    COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1997, 62 : 325 - 336
  • [2] MOUSE BRN-3 FAMILY OF POU TRANSCRIPTION FACTORS - A NEW AMINOTERMINAL DOMAIN IS CRUCIAL FOR THE ONCOGENIC ACTIVITY OF BRN-3A
    THEIL, T
    MCLEANHUNTER, S
    ZORNIG, M
    MOROY, T
    NUCLEIC ACIDS RESEARCH, 1993, 21 (25) : 5921 - 5929
  • [3] Investigating the developmental regulatory role of the class IV POU/brn-3 gene in a sea anemone
    Nakanishi, N.
    INTEGRATIVE AND COMPARATIVE BIOLOGY, 2019, 59 : E375 - E375
  • [4] Embryonic development in the primitive bilaterian Neochildia fusca: normal morphogenesis and isolation of POU genes Brn-1 and Brn-3
    Nallur B. Ramachandra
    Ruth D. Gates
    Peter Ladurner
    David K. Jacobs
    Volker Hartenstein
    Development Genes and Evolution, 2002, 212 : 55 - 69
  • [5] Embryonic development in the primitive bilaterian Neochildia fusca:: normal morphogenesis and isolation of POU genes Brn-1 and Brn-3
    Ramachandra, NB
    Gates, RD
    Ladurner, P
    Jacobs, DK
    Hartenstein, V
    DEVELOPMENT GENES AND EVOLUTION, 2002, 212 (02) : 55 - 69
  • [6] COMPARISON OF THE CHROMOSOMAL LOCALIZATION OF MURINE AND HUMAN GLUCOCEREBROSIDASE GENES AND OF THE DEDUCED AMINO-ACID SEQUENCES
    ONEILL, RR
    TOKORO, T
    KOZAK, CA
    BRADY, RO
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (13) : 5049 - 5053
  • [7] MURINE DEVELOPMENTAL CONTROL GENES
    KESSEL, M
    GRUSS, P
    SCIENCE, 1990, 249 (4967) : 374 - 379
  • [8] Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors
    Morris, PJ
    Lakin, ND
    Dawson, SJ
    Ryabinin, AE
    Kilimann, MW
    Wilson, MC
    Latchman, DS
    MOLECULAR BRAIN RESEARCH, 1996, 43 (1-2): : 279 - 285
  • [9] Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors
    Milton, NGN
    Bessis, A
    Changeux, JP
    Latchman, DS
    BIOCHEMICAL JOURNAL, 1996, 317 : 419 - 423
  • [10] A NOVEL POU FAMILY TRANSCRIPTION FACTOR IS CLOSELY RELATED TO BRN-3 BUT HAS A DISTINCT EXPRESSION PATTERN IN NEURONAL CELLS
    LILLYCROP, KA
    BUDRAHAN, VS
    LAKIN, ND
    TERRENGHI, G
    WOOD, JN
    POLAK, JM
    LATCHMAN, DS
    NUCLEIC ACIDS RESEARCH, 1992, 20 (19) : 5093 - 5096
12345