Fertility Preservation in Girls

被引：22

作者：

Michaeli, Jennia ^{[1
]}

Weintraub, Michael ^{[2
]}

Gross, Eitan ^{[3
]}

Ginosar, Yehuda ^{[4
]}

Ravitsky, Vardit ^{[5
]}

Eizenman, Einat ^{[1
]}

Mitrani, Eduardo ^{[6
]}

Lebovich, Meital ^{[1
]}

Laufer, Neri ^{[1
]}

Kennedy, Stephen ^{[7
]}

Revel, Ariel ^{[1
]}

机构：

[1] Hadassah Hebrew Univ, Med Ctr, Dept Obstet & Gynecol, IL-91120 Jerusalem, Israel

[2] Hadassah Hebrew Univ, Dept Pediat Hematol Oncol, Med Ctr, IL-91120 Jerusalem, Israel

[3] Hadassah Hebrew Univ, Dept Pediat Surg, Med Ctr, IL-91120 Jerusalem, Israel

[4] Hadassah Hebrew Univ, Dept Anesthesiol, Med Ctr, IL-91120 Jerusalem, Israel

[5] Univ Montreal, Bioeth Programs, Fac Med, Montreal, PQ H3C 3J7, Canada

[6] Hebrew Univ Jerusalem, Inst Life Sci, Dept Cell & Dev Biol, IL-91904 Jerusalem, Israel

[7] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Obstet & Gynaecol, Oxford QX1 2JD, England

来源：

OBSTETRICS AND GYNECOLOGY INTERNATIONAL | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/139193

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Children that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal function after resumption of therapy. Effective counseling and management of pediatric patients is crucial for preserving their future reproductive potential. The purpose of this article is to review recent literature and to revise recommendations we made in a 2007 article. Pediatric hemato-oncology, reproductive endocrinology, surgery, anesthesia and bioethics perspectives are discussed and integrated to propose guidelines for offering ovarian cryopreservation to premenarcheal girls with cancer.

引用

页数：10

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