POLAR EFFECTS IN FREE-RADICAL REACTIONS - HOMOLYTIC HETEROAROMATIC SUBSTITUTIONS BY ALKYL BROMIDES

被引：39

作者：

MINISCI, F

FONTANA, F

PIANESE, G

YAN, YM

机构：

[1] Dipartimento di Chimica del Politecnico, 20133 Milano

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 16期

关键词：

D O I：

10.1021/jo00068a013

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkyl bromides have been utilized for the first time as radical sources for heteroaromatic substitution. A variety of Procedures was revealed to be successful for bromine abstraction: Bu3SnH with AIBN, (Me3Si)3SiH with AIBN, PhSiH, Ph2SiH2, or Et3SiH associated with peroxides (H2O2, t-BuOOH, (t-BuO)2, (t-BuOOCO)2, (PhCOO)2). The importance of the polar effects is discussed.

引用

页码：4207 / 4211

页数：5

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