CHANGES IN THE LOW-DENSITY-LIPOPROTEIN PROFILE DURING 17-BETA-ESTRADIOL DYDROGESTERONE THERAPY IN POSTMENOPAUSAL WOMEN

被引：40
|
作者：
VANDERMOOREN, MJ
DEGRAAF, J
DEMACKER, PNM
DEHAAN, AFJ
ROLLAND, R
机构：
[1] UNIV NIJMEGEN ST RADBOUD HOSP, DEPT OBSTET & GYNECOL, 6500 HB NIJMEGEN, NETHERLANDS
[2] UNIV NIJMEGEN ST RADBOUD HOSP, DEPT GEN INTERNAL MED, 6500 HB NIJMEGEN, NETHERLANDS
[3] UNIV NIJMEGEN ST RADBOUD HOSP, DEPT MED STAT, 6500 HB NIJMEGEN, NETHERLANDS
来源：
METABOLISM-CLINICAL AND EXPERIMENTAL | 1994年 / 43卷 / 07期
关键词：
D O I：
10.1016/0026-0495(94)90256-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Changes in the low-density lipoprotein (LDL) subfractions, determined with gradient gel electrophoresis (GGE), were prospectively studied during hormone replacement therapy (HRT) in 23 healthy nonhysterectomized postmenopausal women. LDL subfractions were analyzed by densitometric scanning of the gels. We observed significant changes in the LDL subfraction profile toward a smaller particle size (P < .001). These changes could almost completely be attributed to the hormonal treatment regimen (P < .01), and may indicate an effect partially opposite to the other reported changes in the lipid profile. © 1994.
引用
收藏
页码：799 / 802
页数：4
相关论文
共 50 条
  • [1] INHIBITION OF LOW-DENSITY-LIPOPROTEIN OXIDATION BY 17-BETA-ESTRADIOL
    RIFICI, VA
    CHONG, L
    KHACHADURIAN, AK
    CLINICAL RESEARCH, 1992, 40 (02): : A208 - A208
  • [2] EFFECT OF COMBINED 17-BETA-ESTRADIOL AND VITAMIN-E ON LOW-DENSITY-LIPOPROTEIN OXIDATION IN POSTMENOPAUSAL WOMEN
    GUETTA, V
    PANZA, JA
    WACLAWIW, MA
    CANNON, RO
    AMERICAN JOURNAL OF CARDIOLOGY, 1995, 75 (17): : 1274 - 1276
  • [3] COAGULATION STATUS IN POSTMENOPAUSAL WOMEN USING 17-BETA-ESTRADIOL AND DYDROGESTERONE
    MEIJER, S
    BULLER, HR
    DEBOER, K
    STURK, A
    HAMERLYNCK, JVTH
    THROMBOSIS AND HAEMOSTASIS, 1993, 69 (06) : 629 - 629
  • [4] CHANGES IN THE WITHDRAWAL BLEEDING PATTERN AND ENDOMETRIAL HISTOLOGY DURING 17-BETA-ESTRADIOL DYDROGESTERONE THERAPY IN POSTMENOPAUSAL WOMEN - A 2-YEAR PROSPECTIVE-STUDY
    VANDERMOOREN, MJ
    HANSELAAR, AGJM
    BORM, GF
    ROLLAND, R
    MATURITAS, 1994, 20 (2-3) : 175 - 180
  • [5] THE INHIBITION OF LOW-DENSITY-LIPOPROTEIN OXIDATION BY 17-BETA ESTRADIOL
    RIFICI, VA
    KHACHADURIAN, AK
    METABOLISM-CLINICAL AND EXPERIMENTAL, 1992, 41 (10): : 1110 - 1114
  • [6] 17-BETA-ESTRADIOL PRESERVES ENDOTHELIAL VASODILATOR FUNCTION AND LIMITS LOW-DENSITY-LIPOPROTEIN OXIDATION IN HYPERCHOLESTEROLEMIC SWINE
    KEANEY, JF
    SHWAERY, GT
    XU, AM
    NICOLOSI, RJ
    LOSCALZO, J
    FOXALL, TL
    VITA, JA
    CIRCULATION, 1994, 89 (05) : 2251 - 2259
  • [7] EFFECT OF 17-BETA-ESTRADIOL ON HEPATIC TRIGLYCERIDE LIPASE AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL IN POSTMENOPAUSAL WOMEN
    COLVIN, PL
    AUERBACH, BJ
    APPLEBAUMBOWDEN, D
    MORGAN, T
    HAZZARD, W
    CLINICAL RESEARCH, 1989, 37 (02): : A251 - A251
  • [8] 17-Beta-estradiol therapy lessens angina in postmenopausal women with syndrome X
    Rosano, GMC
    Peters, NS
    Lefroy, D
    Lindsay, DC
    Sarrel, PM
    Collins, P
    PooleWilson, PA
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 28 (06) : 1500 - 1505
  • [9] VASCULAR-RESPONSES TO 17-BETA-ESTRADIOL IN POSTMENOPAUSAL WOMEN
    RIEDEL, M
    OELTERMANN, A
    MUGGE, A
    CREUTZIG, A
    RAFFLENBEUL, W
    LICHTLEN, P
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1995, 25 (01) : 44 - 47
  • [10] HIGH-DENSITY LIPOPROTEIN SUBFRACTIONS DURING ORAL AND CUTANEOUS ADMINISTRATION OF 17-BETA-ESTRADIOL TO MENOPAUSAL WOMEN
    FAHRAEUS, L
    WALLENTIN, L
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 56 (04): : 797 - 801
12345