SYNTHESIS AND CHEMISTRY OF THE INSECT ANTIFEEDANT AZADIRACHTIN

被引:21
|
作者
LEY, SV
机构
[1] Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, Lensfield Road
关键词
D O I
10.1351/pac199466102099
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis of key fragments towards the total synthesis of the insect antifeedant azadirachtin is described, including the decalin portion of this molecule, which was also obtained by natural product degradation using an oxidative and retro-aldol process.
引用
收藏
页码:2099 / 2102
页数:4
相关论文
共 50 条
  • [1] SYNTHESIS AND CHEMISTRY OF THE INSECT ANTIFEEDANT AZADIRACHTIN
    LEY, SV
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 210 : 24 - AGRO
  • [2] Synthesis of Azadirachtin, an Insect Antifeedant
    Mori, Naoki
    Itoh, Daisuke
    Watanabe, Hidenori
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2016, 74 (09) : 903 - 912
  • [3] The Synthesis of Azadirachtin: A Potent Insect Antifeedant
    Ley, Steven V.
    Abad-Somovilla, Antonio
    Anderson, James C.
    Ayats, Caries
    Baenteli, Rolf
    Beckmann, Edith
    Boyer, Alistair
    Brasca, Maria G.
    Brice, Abigail
    Broughton, Howard B.
    Burke, Brenda J.
    Cleator, Ed
    Craig, Donald
    Denholm, Alastair A.
    Denton, Ross M.
    Durand-Reville, Thomas
    Gobbi, Luca B.
    Goebel, Michael
    Gray, Brian Lawrence
    Grossmann, Robert B.
    Gutteridge, Claire E.
    Hahn, Norbert
    Harding, Sarah L.
    Jennens, David C.
    Jennens, Lynn
    Lovell, Peter J.
    Lovell, Helen J.
    de la Puente, Mary L.
    Kolb, Hartmuth C.
    Koot, Win-Jan
    Maslen, Sarah L.
    McCusker, Catherine F.
    Mattes, Amos
    Pape, Andrew R.
    Pinto, Andrea
    Santafianos, Dinos
    Scott, James S.
    Smith, Stephen C.
    Somers, Andrew Q.
    Spilling, Christopher D.
    Stelzer, Frank
    Toogood, Peter L.
    Turner, Richard M.
    Veitch, Gemma E.
    Wood, Anthony
    Zumbrunn, Cornelia
    CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (34) : 10683 - 10704
  • [4] Studies aimed at the total synthesis of azadirachtin as an insect antifeedant
    Murai, A
    JOURNAL OF TOXICOLOGY-TOXIN REVIEWS, 2003, 22 (04): : 617 - 632
  • [5] SYNTHESIS OF A HYDROXY DIHYDROFURAN ACETAL RELATED TO AZADIRACHTIN - A POTENT INSECT ANTIFEEDANT
    LEY, SV
    SANTAFIANOS, D
    BLANEY, WM
    SIMMONDS, MSJ
    TETRAHEDRON LETTERS, 1987, 28 (02) : 221 - 224
  • [6] STRUCTURAL REAPPRAISAL OF THE LIMONOID INSECT ANTIFEEDANT AZADIRACHTIN
    BILTON, JN
    BROUGHTON, HB
    LEY, SV
    LIDERT, Z
    MORGAN, ED
    RZEPA, HS
    SHEPPARD, RN
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1985, (14) : 968 - 971
  • [7] Enantioselective synthesis of the tricyclic furan moiety of azadirachtin, a potent insect antifeedant.
    Watanabe, H
    Watanabe, T
    Mori, K
    TETRAHEDRON, 1996, 52 (44) : 13939 - 13950
  • [8] Synthetic studies on the insect antifeedant terpenes: Azadirachtin and tanabalin
    Watanabe, H
    NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 1999, 73 (02): : 117 - 123
  • [9] A model synthetic approach towards the furanacetal component of azadirachtin: a potent insect antifeedant
    Raina, S
    Prasad, BAB
    Singh, VK
    ARKIVOC, 2003, : 16 - 24
  • [10] Synthesis and insect antifeedant activity of plumbagin derivatives
    Prasad, K. Rajendra
    Babu, K. Suresh
    Rao, R. Ranga
    Suresh, G.
    Rekha, K.
    Murthy, J. Madhusudana
    Rani, P. Usha
    Rao, J. Madhusudana
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (05) : 578 - 583