CLONAL GENE-THERAPY - TRANSPLANTED MOUSE FIBROBLAST CLONES EXPRESS HUMAN ALPHA-1-ANTITRYPSIN GENE INVIVO

被引：115

作者：

GARVER, RI ^{[1
]}

CHYTIL, A ^{[1
]}

COURTNEY, M ^{[1
]}

CRYSTAL, RG ^{[1
]}

机构：

[1] TRANSGENE SA,F-67000 STRASBOURG,FRANCE

来源：

SCIENCE | 1987年 / 237卷 / 4816期

关键词：

D O I：

10.1126/science.3497452

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：762 / 764

页数：3

共 26 条

[1] PROSPECTS FOR HUMAN-GENE THERAPY [J].

ANDERSON, WF .

SCIENCE, 1984, 226 (4673) :401-409

[2]

ARMENTANO D, IN PRESS J VIROL

[3]

BIETH J, 1978, FRONTIERS MATRIX BIO, V6, P1

[4] ALPHA-1-ANTITRYPSIN - MOLECULAR PATHOLOGY, LEUKOCYTES, AND TISSUE-DAMAGE [J].

CARRELL, RW .

JOURNAL OF CLINICAL INVESTIGATION, 1986, 78 (06) :1427-1431

[5] A VIRAL LONG TERMINAL REPEAT IN THE INTERLEUKIN-2 GENE OF A CELL-LINE THAT CONSTITUTIVELY PRODUCES INTERLEUKIN-2 [J].

CHEN, SJ ;

HOLBROOK, NJ ;

MITCHELL, KF ;

VALLONE, CA ;

GREENGARD, JS ;

CRABTREE, GR ;

LIN, Y .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (21) :7284-7288

[6] HIGH-LEVEL PRODUCTION OF BIOLOGICALLY-ACTIVE HUMAN ALPHA-1-ANTITRYPSIN IN ESCHERICHIA-COLI [J].

COURTNEY, M ;

BUCHWALDER, A ;

TESSIER, LH ;

JAYE, M ;

BENAVENTE, A ;

BALLAND, A ;

KOHLI, V ;

LATHE, R ;

TOLSTOSHEV, P ;

LECOCQ, JP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (03) :669-673

[7]

Gadek J., 1982, METABOLIC BASIS INHE, P1450

[8] ANTI-ELASTASES OF THE HUMAN ALVEOLAR STRUCTURES - IMPLICATIONS FOR THE PROTEASE-ANTIPROTEASE THEORY OF EMPHYSEMA [J].

GADEK, JE ;

FELLS, GA ;

ZIMMERMAN, RL ;

RENNARD, SI ;

CRYSTAL, RG .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (04) :889-898

[9] REPLACEMENT THERAPY OF ALPHA-1-ANTITRYPSIN DEFICIENCY - REVERSAL OF PROTEASE-ANTIPROTEASE IMBALANCE WITHIN THE ALVEOLAR STRUCTURES OF PIZ SUBJECTS [J].

GADEK, JE ;

KLEIN, HG ;

HOLLAND, PV ;

CRYSTAL, RG .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (05) :1158-1165

[10] PRODUCTION OF GLYCOSYLATED PHYSIOLOGICALLY NORMAL HUMAN ALPHA-1-ANTITRYPSIN BY MOUSE FIBROBLASTS MODIFIED BY INSERTION OF A HUMAN ALPHA-1-ANTITRYPSIN CDNA USING A RETROVIRAL VECTOR [J].

GARVER, RI ;

CHYTIL, A ;

KARLSSON, S ;

FELLS, GA ;

BRANTLY, ML ;

COURTNEY, M ;

KANTOFF, PW ;

NIENHUIS, AW ;

ANDERSON, WF ;

CRYSTAL, RG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (04) :1050-1054

← 1 2 3 →