LARGE-SCALE PURIFICATION AND CHARACTERIZATION OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF LACTOBACILLUS-CASEI

被引：154
作者：
DANN, JG
OSTLER, G
BJUR, RA
KING, RW
SCUDDER, P
TURNER, PC
ROBERTS, GCK
BURGEN, ASV
HARDING, NGL
机构：
[1] POSTGRAD MED SCH,CAMBRIDGE CB2 1QT,ENGLAND
[2] NATL INST MED RES,DIV MOLEC PHARMACOL,LONDON NW7 1AA,ENGLAND
来源：
BIOCHEMICAL JOURNAL | 1976年 / 157卷 / 03期
关键词：
D O I：
10.1042/bj1570559
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：559 / 571
页数：13
相关论文
共 48 条
[1]   FOLATE REDUCTASE AND SPECIFIC DIHYDROFOLATE REDUCTASE ACTIVITIES OF AMETHOPTERIN-SENSITIVE STREPTOCOCCUS FAECIUM VAR. DURANS [J].
ALBRECHT, AM ;
HUTCHISON, DJ .
JOURNAL OF BACTERIOLOGY, 1969, 100 (01) :533-+
[2]   PRECIPITATION OF NUCLEIC-ACIDS WITH POLYETHYLENEIMINE AND CHROMATOGRAPHY OF NUCLEIC-ACIDS AND PROTEINS ON IMMOBILIZED POLYETHYLENEIMINE [J].
ATKINSON, A ;
JACK, GW .
BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 308 (01) :41-52
[3]  
Baker BR, 1967, DESIGN ACTIVE SITE D
[4]   DIHYDROFOLATE-REDUCTASE FROM BOVINE LIVER - ENZYMATIC AND STRUCTURAL-PROPERTIES [J].
BAUMANN, H ;
WILSON, KJ .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1975, 60 (01) :9-15
[5]   REACTION OF TETRAHYDROPTEROYLGLUTAMIC ACID AND RELATED HYDROPTERIDINES WITH FORMALDEHYDE [J].
BLAKLEY, RL .
BIOCHEMICAL JOURNAL, 1959, 72 :707-715
[6]  
BLAKLEY RL, 1969, BIOCHEMISTRY FOLIC A
[7]  
BURCHALL JJ, 1965, MOL PHARMACOL, V1, P126
[8]  
BURCHALL JJ, 1969, FED PROC, V28, P352
[9]   IMPROVED PURIFICATION OF TETRAHYDROFOLATE DEHYDROGENASE FROM L1210 LEUKEMIA BY AFFINITY CHROMATOGRAPHY [J].
CHELLO, PL ;
CASHMORE, AR ;
BERTINO, JR ;
JACOBS, SA .
BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 268 (01) :30-&
[10]   SINGLE-STEP PURIFICATION OF DIHYDROFOLATE REDUCTASES ON PTERIDINE MATRICES [J].
DANN, JG ;
WHITELEY, JM ;
NEWBOLD, PCH ;
HARDING, NGL .
BIOCHEMICAL JOURNAL, 1972, 127 (02) :P28-&
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