EXAMINATION OF THE DISTURBANCE IN ENERGETIC METABOLISM OF EHRLICH ASCITE CARCINOMA-CELLS DURING ANTITUMOR DRUG INFLUENCE USING HIGH-RESOLUTION P-31-NMR

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作者
SEMENOVA, NA
SHELOK, EP
OSTROVSKAYA, LA
SIBELDINA, LA
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Q [生物科学];
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07 ; 0710 ; 09 ;
摘要
The disturbance in energetic metabolism of Ehrlich ascite carcinoma cells during antitumor drug treatment was examined using nigh resolution P-31-NMR. The value of antitumor drug effect was shown to be characterized by the kinetics of ATP and KF level alteration in tumor cells. The results correlated with the indexes of therapeutical activity of studied drugs.
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页码:794 / 798
页数:5
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