LIGAND-BINDING TO ADENOSINE-A1-RECEPTORS IS INFLUENCED BY PROTONATION

被引：4
|
作者：
HOPPE, E
REDDINGTON, M
机构：
[1] Department of Neuromorphology, Max Planck Institute for Psychiatry
来源：
NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 05期
关键词：
D O I：
10.1080/07328319108047255
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Studies on the pH dependence of ligand binding to A1 adenosine receptors revealed that protonation of a histidine residue in the binding pocket is accompanied by high affinity agonist binding.
引用
收藏
页码：1139 / 1140
页数：2
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