Comparison of Spectral Domain Optical Coherence Tomography and Ultrasonic Pachymetry for Assessment of Central Corneal Thickness

Objectives: The aim of this study was to determine if there is a difference in central corneal thickness (CCT) measurements obtained by Cirrus spectral domain optical coherence tomography (SD-OCT) and ultrasonic pachymetry in healthy individuals. Materials and Methods: The study included 50 healthy consecutively selected individuals without ocular or systemic disease. CCT was first measured using OCT, and then using ultrasonic pachymetry. Results: Mean age of the participants was 31.44 years. Mean CCT measured using SD-OCT was 531.78 mu m versus 535.15 mu m by ultrasonic pachymetry. Mean CCT measurement obtained by Cirrus SD-OCT showed statistically significant difference by approximately 3.37 mu m than the one obtained by ultrasonic pachymetry (t-test, p<0.05); however, Bland-Altman analysis proved that there was high concordance between the measurements. Conclusion: CCT measurements obtained by Cirrus SD-OCT were very similar to those obtained by ultrasonic pachymetry, and as such we think that Cirrus SD-OCT can be used in our present ophthalmology practice to measure OCT.