4,5-DIHYDROXY-2-HEXANONE - A NEW METABOLITE OF N-HEXANE AND OF 2,5-HEXANEDIONE IN RAT URINE

被引：18
|
作者：
FEDTKE, N [1 ]
BOLT, HM [1 ]
机构：
[1] UNIV DORTMUND,INST ARBEITSPHYSIOL,TOXIKOL & ARBEITSMED ABT,ARDEYSTR 67,D-4600 DORTMUND 50,FED REP GER
来源：
BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY | 1987年 / 14卷 / 10期
关键词：
D O I：
10.1002/bms.1200141006
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
引用
收藏
页码：563 / 572
页数：10
相关论文
共 50 条
  • [1] DETERMINATION OF 2,5-HEXANEDIONE, A METABOLITE OF N-HEXANE, IN URINE - EVALUATION AND APPLICATION OF 3 ANALYTICAL METHODS
    VANENGELEN, JGM
    KEZIC, S
    DEHAAN, W
    OPDAM, JJG
    DEWOLFF, FA
    JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS, 1995, 667 (02): : 233 - 240
  • [2] Evaluation of 2,5-hexanedione in urine of workers exposed to n-hexane in Brazilian shoe factories
    dos Santos, CR
    Passarelli, MM
    Nascimento, ED
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 778 (1-2): : 237 - 244
  • [3] Comparison of unchanged n-hexane in alveolar air and 2,5-hexanedione in urine for the biological monitoring of n-hexane exposure in human volunteers
    G. Hamelin
    G. Truchon
    R. Tardif
    International Archives of Occupational and Environmental Health, 2004, 77 : 264 - 270
  • [4] THE RELEVANCE OF 4,5-DIHYDROXY-2-HEXANONE IN THE EXCRETION KINETICS OF NORMAL-HEXANE METABOLITES IN RAT AND MAN
    FEDTKE, N
    BOLT, HM
    ARCHIVES OF TOXICOLOGY, 1987, 61 (02) : 131 - 137
  • [5] Comparison of unchanged n-hexane in alveolar air and 2,5-hexanedione in urine for the biological monitoring of n-hexane exposure in human volunteers
    Hamelin, G
    Truchon, G
    Tardif, R
    INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2004, 77 (04) : 264 - 270
  • [6] BIOLOGICAL MONITORING OF OCCUPATIONAL EXPOSURE TO N-HEXANE BY MEASUREMENT OF URINARY 2,5-HEXANEDIONE
    CARDONA, A
    MARHUENDA, D
    MARTI, J
    BRUGNONE, F
    ROEL, J
    PERBELLINI, L
    INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 1993, 65 (01) : 71 - 74
  • [7] Urinary 2,5-hexanedione in workers exposed to N-hexane: Influence of the sample treatment
    Nolasco, Daniela Magalhaes
    Gusmao, Andreia
    Pereira Bastos de Siqueira, Maria Elisa
    QUIMICA NOVA, 2007, 30 (04): : 805 - 808
  • [8] THE METHOD OF CHOICE FOR THE DETERMINATION OF 2,5-HEXANEDIONE AS AN INDICATOR OF OCCUPATIONAL EXPOSURE TO N-HEXANE
    KAWAI, T
    MIZUNUMA, K
    YASUGI, T
    UCHIDA, Y
    IKEDA, M
    INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 1990, 62 (05) : 403 - 408
  • [9] COVALENT BINDING OF A NEUROTOXIC N-HEXANE METABOLITE - CONVERSION OF PRIMARY AMINES TO SUBSTITUTED PYRROLE ADDUCTS BY 2,5-HEXANEDIONE
    DECAPRIO, AP
    OLAJOS, EJ
    WEBER, P
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 1982, 65 (03) : 440 - 450
  • [10] TOXICITY AND METABOLISM OF THE NEUROTOXIC HEXACARBONS NORMAL-HEXANE, 2-HEXANONE, AND 2,5-HEXANEDIONE
    COURI, D
    MILKS, M
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1982, 22 : 145 - 166
12345