RESTRICTION FRAGMENT LENGTH POLYMORPHISMS IN THE ETS-1 PROTO-ONCOGENE - COMPARISON OF SAUDI AND WESTERN POPULATIONS

被引：1
|
作者：
PARKAR, MH
SEID, JM
ROWSON, JM
STRINGER, BM
VENCER, LJ
AUR, RJA
GOYNS, MH
机构：
[1] KING FAISAL SPECIALIST HOSP & RES CTR, DEPT BIOL & MED RES, RIYADH 11211, SAUDI ARABIA
[2] KING FAISAL SPECIALIST HOSP & RES CTR, DEPT ONCOL, RIYADH 11211, SAUDI ARABIA
来源：
EXPERIENTIA | 1988年 / 44卷 / 11-12期
关键词：
D O I：
10.1007/BF01939909
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We have cloned part of the ETS 1 proto-oncogene and demonstrated the presence of two polymorphic Sst I restriction sites. A probe derived from one of our clones revealed the presence of 8.3 kb, 9.5 kb and/or 11.5 kb fragments on Southern blots of human DNA samples. The relative frequencies of these alleles appear to be significantly different between Saudi and Western populations, but there are no apparent differences in these frequencies between Saudi non-leukemic and leukemic individuals.
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收藏
页码：1019 / 1020
页数：2
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