Multipotent stem cells of mother's milk

被引:13
|
作者
Reali, Alessandra [1 ,2 ]
Puddu, Melania [1 ,2 ]
Pintus, Maria Cristina [1 ,2 ]
Marcialis, Maria Antonietta [1 ,2 ]
Pichiri, Giuseppina [3 ]
Coni, Pierpaolo [3 ]
Manus, Danila [1 ,2 ]
Dess, Angelica [1 ,2 ]
Faa, Gavino [3 ]
Fanos, Vassilios [1 ,2 ,4 ]
机构
[1] AOU, Inst Puericulture, Neonatal Pathol, Neonatal Intens Care Unit, Cagliari, Italy
[2] AOU, Neonatal Sect, Cagliari, Italy
[3] Univ Cagliari, Sect Pathol, Dept Surg Sci, Cagliari, Italy
[4] Univ Cagliari, Cagliari, Italy
来源
JOURNAL OF PEDIATRIC AND NEONATAL INDIVIDUALIZED MEDICINE | 2016年 / 5卷 / 01期
关键词
Human breastmilk-derived stem cells (hBSCs); epithelial progenitors; mesenchymal stem cells; embryonic stem cells;
D O I
10.7363/050103
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
In recent years the presence of stem cells (hBSCs: human breastmilk-derived stem cells) and epithelial progenitors has been demonstrated in mother's milk (MM). Stem cells present in samples of fresh MM exhibit a high degree of vitality and this makes possible the performance of cell cultures and to evaluate the differentiation capacity of the hBSCs. The most important datum that expresses the enormous potential of the use of MM stem cells is the presence of a cell population capable of differentiating into the three mesoderm, endoderm and ectoderm lines. The small number of studies and MM samples analyzed and the different sampling methods applied suggest standardization in the collection, analysis and culture of MM in future studies, in consideration of the well-known extreme variability of MM composition, also from the standpoint of cells. The analysis of literature data confirms the uniqueness of MM and its enormous potential.
引用
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页数:5
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