CYTOSINE-ARABINOSIDE AND CISPLATIN FOR ADVANCED BREAST-CANCER - A PHASE-II STUDY OF THE CANCER AND LEUKEMIA GROUP-B

被引：0

作者：

OSTER, MW

SCHILSKY, RL

FARAGGI, D

KORZUN, AH

PERRY, M

MOORE, A

KALRA, J

WOOD, WC

HENDERSON, IC

机构：

[1] LONG ISL JEWISH MED CTR,NEW HYDE PK,NY

[2] COLUMBIA UNIV COLL PHYS & SURG,NEW YORK,NY 10032

[3] CORNELL UNIV,MED CTR,COLL MED,NEW YORK,NY 10021

[4] UNIV CHICAGO,PRITZKER SCH MED,CHICAGO,IL 60637

[5] HARVARD UNIV,SCH PUBL HLTH,BOSTON,MA 02115

[6] HARVARD UNIV,SCH MED,BOSTON,MA 02115

[7] UNIV MISSOURI,MED CTR,SCH MED,COLUMBIA,MO 65201

来源：

CANCER | 1991年 / 68卷 / 08期

关键词：

D O I：

10.1002/1097-0142(19911015)68:8<1696::AID-CNCR2820680807>3.0.CO;2-B

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Forty-four women with advanced breast cancer participated in a prospective clinical trial to evaluate the efficacy and toxicity of a regimen consisting of cytosine arabinoside and cisplatin. All patients had previously received chemotherapy. Three patients (7%) responded to therapy with response durations of 153, 160, and 441 days. The median time to disease progression and median survival time in all 44 patients were 2.3 and 5 months, respectively. This regimen had significant toxicity, with most patients experiencing severe or life-threatening hematologic, renal, or infectious complications. This regimen cannot be recommended for previously treated patients with advanced breast cancer.

引用

页码：1696 / 1698

页数：3

共 50 条

[1] AZIRIDINYLBENZOQUINONE (AZQ) IN ADVANCED BREAST-CANCER - A CANCER AND LEUKEMIA GROUP-B PHASE-II TRIAL
BUDMAN, DR
FORASTIERE, A
PERLOFF, M
PERRY, M
AISNER, J
WEINBERG, V
WOOD, W
CANCER TREATMENT REPORTS, 1982, 66 (10): : 1875 - 1876
[2] PHASE-II STUDY OF AMSA IN PATIENTS WITH METASTATIC BREAST-CANCER - A CANCER AND LEUKEMIA GROUP-B STUDY
AMREIN, PC
COLEMAN, M
RICHARDS, F
POULIN, RF
BERNHARDT, B
GINSBERG, SJ
GREEN, MR
MORRISON, A
CORTES, E
KIANG, D
WEINBERG, V
WOOD, WC
CANCER TREATMENT REPORTS, 1982, 66 (05): : 1211 - 1213
[3] PHASE-II STUDY OF ECHINOMYCIN IN PATIENTS WITH ADVANCED BREAST-CANCER - A REPORT OF CANCER AND LEUKEMIA GROUP-B PROTOCOL 8641
SCHILSKY, RL
FARAGGI, D
KORZUN, A
VOGELZANG, N
ELLERTON, J
WOOD, W
HENDERSON, IC
INVESTIGATIONAL NEW DRUGS, 1991, 9 (03) : 269 - 272
[4] CISPLATIN IN PATIENTS WITH GASTRIC-CANCER - A CANCER AND LEUKEMIA GROUP-B PHASE-II STUDY
PERRY, MC
GREEN, MR
MICK, R
SCHEIN, P
CANCER TREATMENT REPORTS, 1986, 70 (03): : 415 - 416
[5] PHASE-II TRIAL OF ACLARUBICIN IN ADVANCED BREAST-CANCER - A CANCER-AND-LEUKEMIA-GROUP-B STUDY
FORASTIERE, AA
BUDMAN, DR
RICHARDS, F
AISNER, J
WEINBERG, V
WOOD, WC
CANCER TREATMENT REPORTS, 1983, 67 (12): : 1137 - 1138
[6] PHASE-II TRIAL OF CARBOPLATIN IN ADVANCED BREAST-CARCINOMA - A CANCER AND LEUKEMIA GROUP-B STUDY
BOOTH, BW
WEISS, RB
KORZUN, AH
WOOD, WC
CAREY, RW
PANASCI, LC
CANCER TREATMENT REPORTS, 1985, 69 (7-8): : 919 - 920
[7] PHASE-II TRIAL OF ACIVICIN IN ADVANCED BREAST-CARCINOMA - A CANCER AND LEUKEMIA GROUP-B STUDY
BOOTH, BW
KORZUN, AH
WEISS, RB
ELLISON, RR
BUDMAN, D
KHOJASTEH, A
WOOD, W
CANCER TREATMENT REPORTS, 1986, 70 (10): : 1247 - 1248
[8] PHASE-II TRIAL OF SPIROGERMANIUM IN BREAST ADENOCARCINOMA - A CANCER AND LEUKEMIA GROUP-B STUDY
BUDMAN, DR
GINSBERG, S
PERRY, M
WEINBERG, V
SCHEIN, P
HANSON, J
COLEMAN, M
WOOD, W
CANCER TREATMENT REPORTS, 1982, 66 (08): : 1667 - 1668
[9] PHASE-II TRIAL OF BISANTRENE IN ADVANCED COLORECTAL-CANCER - A CANCER AND LEUKEMIA GROUP-B STUDY
PERRY, MC
FORASTIERE, AA
RICHARDS, F
WEISS, RB
ANBAR, D
CANCER TREATMENT REPORTS, 1982, 66 (11): : 1997 - 1998
[10] CISPLATIN PLUS VINDESINE IN ADVANCED BREAST-CANCER - A PHASE-II TRIAL OF THE EORTC BREAST-CANCER COOPERATIVE GROUP
PARIDAENS, R
CLARYSSE, A
ROZENCWEIG, M
ROTMENSZ, N
HEUSON, JC
EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1985, 21 (05): : 595 - 599

← 1 2 3 4 5 →