METABOLISM OF BENZO[C]PHENANTHRENE BY RAT-LIVER MICROSOMES AND BY A PURIFIED MONOOXYGENASE SYSTEM RECONSTITUTED WITH DIFFERENT ISOZYMES OF CYTOCHROME-P-450

被引：47
|
作者：
ITTAH, Y [1 ]
THAKKER, DR [1 ]
LEVIN, W [1 ]
CROISYDELCEY, M [1 ]
RYAN, DE [1 ]
THOMAS, PE [1 ]
CONNEY, AH [1 ]
JERINA, DM [1 ]
机构：
[1] HOFFMANN LA ROCHE INC, DEPT BIOCHEM & DRUG METAB, NUTLEY, NJ 07110 USA
来源：
CHEMICO-BIOLOGICAL INTERACTIONS | 1983年 / 45卷 / 01期
关键词：
D O I：
10.1016/0009-2797(83)90039-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：15 / 28
页数：14
相关论文
共 50 条
  • [1] RAT-LIVER CYTOCHROME-P-450 ISOZYMES AS CATALYSTS OF ALDRIN EPOXIDATION IN RECONSTITUTED MONOOXYGENASE SYSTEMS AND MICROSOMES
    WOLFF, T
    GUENGERICH, FP
    BIOCHEMICAL PHARMACOLOGY, 1987, 36 (16) : 2581 - 2588
  • [2] METABOLISM OF DICHLOROBIPHENYLS BY HIGHLY PURIFIED ISOZYMES OF RAT-LIVER CYTOCHROME-P-450
    KAMINSKY, LS
    KENNEDY, MW
    ADAMS, SM
    GUENGERICH, FP
    BIOCHEMISTRY, 1981, 20 (26) : 7379 - 7384
  • [3] METABOLISM OF LIDOCAINE BY PURIFIED RAT-LIVER MICROSOMAL CYTOCHROME-P-450 ISOZYMES
    ODA, Y
    IMAOKA, S
    NAKAHIRA, Y
    ASADA, A
    FUJIMORI, M
    FUJITA, S
    FUNAE, Y
    BIOCHEMICAL PHARMACOLOGY, 1989, 38 (24) : 4439 - 4444
  • [4] STEREOSELECTIVE METABOLISM OF (+)-BENZO[A]ANTHRACENE 3,4-DIHYDRODIOLS BY RAT-LIVER MICROSOMES AND A RECONSTITUTED CYTOCHROME-P-450 SYSTEM
    THAKKER, DR
    LEVIN, W
    YAGI, H
    TADA, M
    RYAN, DE
    THOMAS, PE
    CONNEY, AH
    JERINA, DM
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1981, 22 (MAR): : 98 - 98
  • [5] METABOLISM OF METHYL-N-AMYLNITROSAMINE (MNAN) BY RAT-LIVER MICROSOMES AND A RECONSTITUTED CYTOCHROME-P-450 SYSTEM
    JI, C
    MIRVISH, SS
    ICHIZUKI, H
    LEE, MJ
    YANG, CS
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1988, 29 : 123 - 123
  • [6] ROLE OF RAT-LIVER CYTOCHROME-P-450 ISOZYMES IN NICOTINE METABOLISM
    BJERCKE, RJ
    HAMMOND, DK
    STROBEL, MW
    LANGONE, JJ
    FASEB JOURNAL, 1991, 5 (06): : A1519 - A1519
  • [7] METABOLISM AND ACTIVATION OF AFLATOXIN-B1 IN NUCLEI, MICROSOMES AND RECONSTITUTED CYTOCHROME-P-450 SYSTEM OF RAT-LIVER
    YOSHIZAWA, H
    KUBO, R
    UENO, Y
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1981, 4 (04): : S44 - S44
  • [8] METABOLISM OF ALPHA-NAPHTHOFLAVONE AND BETA-NAPHTHOFLAVONE BY RAT-LIVER MICROSOMES AND HIGHLY PURIFIED RECONSTITUTED CYTOCHROME-P-450 SYSTEMS
    VYAS, KP
    SHIBATA, T
    HIGHET, RJ
    YEH, HJ
    THOMAS, PE
    RYAN, DE
    LEVIN, W
    JERINA, DM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1983, 258 (09) : 5649 - 5659
  • [9] IDENTIFICATION OF CYTOCHROME-P-450 ISOZYMES INVOLVED IN THE HYDROXYLATION OF DANTROLENE BY RAT-LIVER MICROSOMES
    JAYYOSI, Z
    VILLOUTREIX, J
    ZIEGLER, JM
    BATT, AM
    DEMAACK, F
    SIEST, G
    THOMAS, PE
    DRUG METABOLISM AND DISPOSITION, 1993, 21 (05) : 939 - 945
  • [10] SUBSTRATE SPECIFICITIES AND STEREOSELECTIVITIES OF 7 PURIFIED ISOZYMES OF RAT-LIVER CYTOCHROME-P-450
    KAMINSKY, LS
    GUENGERICH, FP
    FEDERATION PROCEEDINGS, 1982, 41 (04) : 1296 - 1296
12345