LOCALIZATION OF CHROMATIN IN PERSISTENT NUCLEOLI IN OKADAIC ACID-TREATED HELA-CELLS

被引:6
|
作者
GHOSH, S
PAWELETZ, N
机构
[1] UNIV CALCUTTA,CTR ADV STUDY BOT,CALCUTTA 700019,W BENGAL,INDIA
[2] GERMAN CANC RES CTR,INST CELL & TUMOR BIOL,NEUENHEIMER FELD 280,W-6900 HEIDELBERG,GERMANY
关键词
D O I
10.1016/S0309-1651(06)80066-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In okadaic acid treated HeLa cells, the chromosomes sometimes condense without being accompanied by nuclear envelope breakdown. These cells show "persistent" nucleoli. Within these "persistent" nucleoli the intranucleolar chromatin condenses and can be observed in the region of the dense nucleolar component (DNC) of the nucleoli. Other nucleolar components, namely the fibrillar centre (FC) and the granular component (GC) remain unchanged. These observations strongly speak for the localization of nucleolar chromatin (ribosomal cistrons) within the dense nucleolar component of the interphase nucleolus. © 1992 Academic Press Ltd.
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页码:475 / 480
页数:6
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