EXPRESSION OF HUMAN ATRIAL NATRIURETIC POLYPEPTIDE GENE IN COS-7 CELLS

被引：2
|
作者：
IWAI, N [1 ]
MATSUNAGA, M [1 ]
OGAWA, K [1 ]
MATSUMORI, A [1 ]
YOSHIDA, H [1 ]
OHTA, E [1 ]
KAWAI, C [1 ]
机构：
[1] KYOTO UNIV, DEPT PATHOL, DIV 2, KYOTO 606, JAPAN
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1987年 / 143卷 / 01期
关键词：
D O I：
10.1016/0006-291X(87)90663-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cos 7 cells transfected with human atrial natriuretic polypeptide (hANP) gene with SV40 enhancer and replication origin sequences expressed hANP gene. The expressed RNA was indistinguishable from native hANP mRNA and the transcribed protein seemed to be properly processed to .alpha.-hANP and .beta.-hANP. This system provides a useful approach to investigate the processing of hANPs and the structure-function relationship of amino acid sequences of hANPs.
引用
收藏
页码：288 / 293
页数：6
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