A HIGHLY EFFICIENT SYNTHESIS OF RWJ-47639 - A NOVEL, ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONIST

被引：3
|
作者：
HSI, JD
MURRAY, WV
GILL, A
机构：
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 08期
关键词：
D O I：
10.1016/S0960-894X(00)80010-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
RWJ 47639 (1), a new, potent and orally active angiotensin II receptor antagonist was synthesized by an efficient three-step process utilizing addition of a substituted phenyllithium to an ortho-fluorophenyloxazoline as the key step.
引用
收藏
页码：1523 / 1526
页数：4
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