Severe Acute Hepatitis B Treated With Entecavir

被引：11
|
作者：
De Socio, Giuseppe Vittorio Luigi [1 ]
Sgrelli, Alessio [1 ]
Tosti, Andrea [1 ]
Baldelli, Franco [1 ]
机构：
[1] Univ Perugia, Santa Maria Misericordia Hosp, Dept Infect Dis, Perugia, Italy
来源：
MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES | 2011年 / 3卷 / 01期
关键词：
D O I：
10.4084/MJHID.2011.010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of hepatitis B surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody anti-HBs appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases.
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页数：4
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