SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-4-HYDROXYPIPERIDINE DERIVATIVES

被引：0
|
作者：
YESENALIYEVA, MZ [1 ]
KURBAT, NM [1 ]
PRALIYEV, KD [1 ]
KOZLOVSKY, VI [1 ]
YU, VK [1 ]
VDOVICHENKO, VP [1 ]
机构：
[1] GRODNO MED INST, GRODNO, BELORUSSIA, BELARUS
来源：
KHIMIKO-FARMATSEVTICHESKII ZHURNAL | 1991年 / 25卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
1-]2-(3,4-Dimethoxyphenyl)ethyl]-4-hydroxypiperidine and its 4-acet-(propionyl- and benzoyl-)esters were synthesized. Benzoyl ester was found to have a local anesthetic and antihypoxic (barochamber) action.
引用
收藏
页码：22 / 24
页数：3
相关论文
共 50 条
  • [1] NEW DERIVATIVES OF 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-2-METHYL-4-ETHYNYL-4-HYDROXY-TRANS-DECAHYDROQUINOLINE STEREOISOMERS - SYNTHESIS AND CARDIOTROPIC ACTIVITY
    PRALIEV, KD
    FISHCHUK, EV
    MALCHIKOVA, LS
    ORANOVSKAYA, EV
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1989, 23 (08): : 939 - 941
  • [2] STEREOISOMERIC 1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-2-METHYL-4-ETHYNYL-4-ACYLOXY-TRANS-DECAHYDROQUINOLINES - SYNTHESIS AND CARDIOTROPIC ACTIVITY
    FISHCHUK, EV
    PRALIYEV, KD
    MALCHIKOVA, LS
    ORANOVSKAYA, EV
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1989, 23 (08): : 936 - 938
  • [3] Synthesis and pharmacological activity of 4-(4′-(chlorophenyl)-4-hydroxypiperidine) derivatives
    Saify, ZS
    Mushtaq, N
    Khan, KM
    Perveen, S
    Shah, STA
    Abdel-Jalil, RJ
    Fecker, M
    Voelter, W
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (01) : 64 - 66
  • [4] 2-(3,4-Dimethoxyphenyl)ethyl](3-{N-[2(3,4-dimethoxyphenyl)ethyl]carbamoyl}-propyl)azanium chloride dihydrate
    Saidov, Abdusalom Sh.
    Turgunov, Kambarali K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : 0232 - +
  • [5] Synthesis, characterization and antimicrobial activity studies of 1-& 2-[{2-(3,4-dimethoxyphenyl)ethyl}methylamino]sulphonyl naphthalenes
    Dayalan, A.
    Babu, C. Suneel Manohar
    Visweswaran, V.
    ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (02) : 1411 - 1419
  • [6] O-ethyl S-[1-(3,4-dimethoxyphenyl)-2-(hydroxyimino)propyl] dithiocarbonate
    Hartung, J
    Daniel, K
    Svoboda, I
    Fuess, H
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O3437 - O3439
  • [7] AN EFFICIENT SYNTHESIS OF 2-(3,4-DIMETHOXYPHENYL)SUCCINIMIDE
    CLAUDI, F
    GULINI, U
    PERLINI, V
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1987, 19 (01) : 61 - 63
  • [8] Synthesis of 4-hydroxypiperidine derivatives and their screening for analgesic activity
    Saeed, M
    Saify, ZS
    Iqbal, Z
    NazarulIslam
    ARCHIVES OF PHARMACAL RESEARCH, 1997, 20 (04) : 338 - 341
  • [9] (E)-1-(2-BROMO-4,5-DIMETHOXYPHENYL)-2-(3,4-DIMETHOXYPHENYL)ETHYLENE
    ARRIETA, JM
    LETE, E
    DOMINGUEZ, E
    GERMAIN, G
    DECLERCQ, JP
    AMIGO, JM
    ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1982, 38 (DEC): : 3155 - 3157
  • [10] N-[2-(3,4-Dimethoxyphenyl)ethyl]-N,4-dimethylbenzenesulfonamide
    Vennila, Jasmine P.
    Thiruvadigal, D. John
    Kavitha, Helen P.
    Chakkaravarthi, G.
    Manivannan, V.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2186 - U1881
12345