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THE DETECTION OF AGE-RELATED DECREASE OF DOPAMINE-D1, DOPAMINE-D2 AND SEROTONIN 5-HT2 RECEPTORS IN LIVING HUMAN BRAIN
被引:49
|作者:
IYO, M
YAMASAKI, T
机构:
[1] Division of Clinical Research, National Institute of Radiological Sciences, Chiba-shi, Chiba
[2] Division of Drug Dependence and Psychotropic Clinical Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ichikawa-shi, Chiba
来源:
关键词:
POSITRON EMISSION TOMOGRAPHY;
RECEPTOR IMAGING;
AGE;
DOPAMINE RECEPTORS;
SEROTONIN RECEPTORS;
D O I:
10.1016/0278-5846(93)90075-4
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
1. Using positron emission tomography and C-11-N-methylspiperone and C-11- SCH23390, dopamine D1 and D2 receptors, and serotonin 5-HT2 receptors in human brain were evaluated in living healthy age different subjects. 2. Dynamic analysis of PET data indicated that these receptor binding abilities decreased with aging in healthy humans.
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页码:415 / 421
页数:7
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