RABBIT ANTIBODY-RESPONSES TO EXPERIMENTAL INFESTATION WITH DERMATOBIA-HOMINIS

被引:5
|
作者
DELELLO, E [1 ]
BOULARD, C [1 ]
机构
[1] UNIV NACL ESTADUAL SAO PAULO,INST BIOSCI,BR-18600 SAO PAULO,BRAZIL
关键词
bot fly; Dermatobia hominis; ELISA; experimental infestation; immunodiagnosis; immunodiffusion techniques;
D O I
10.1111/j.1365-2915.1990.tb00444.x
中图分类号
Q96 [昆虫学];
学科分类号
摘要
Abstract. The three larval stages of Dermatobia hominis (Linnaeus) have been evaluated for their immunogenicity by ELISA and immunodiffusion (ID) using sera from experimentally infested rabbits. During a primary infestation, first instar D.hominis were found to cause most reaction and allowed the earliest diagnosis by ELISA. An inhibition of the antibody response against second and third instars was observed. The inhibition disappeared after departure of the larvae from the host. In experimentally immunized hosts the antibody response, following challenge, was highest against second and third instar antigens. Antibody remained elevated during the infestation but fell immediately after the larvae had left the host. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
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页码:303 / 309
页数:7
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