PREPARATION OF ALLYLIC ALCOHOLS BY ALKENE TRANSFER FROM ZIRCONIUM TO ZINC

被引：157
|
作者：
WIPF, P
XU, WJ
机构：
[1] Department of Chemistry, University of Pittsburgh, Pittsburgh
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 29期
关键词：
D O I：
10.1016/S0040-4039(00)77062-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Transmetalation of alkenyl zirconocenes 2 to the corresponding organozinc compounds 3 occurs rapidly and at low temperature in the presence of stoichiometric amounts of commercially available dimethyl- or diethylzinc. Subsequent addition of aldehydes provides an in situ protocol for the conversion of alkynes 1 into allylic alcohols 5 in good to excellent yields.
引用
收藏
页码：5197 / 5200
页数：4
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