ION-SOURCE FOR LIQUID MATRIX SECONDARY IONIZATION MASS-SPECTROMETRY

被引：77
作者：
FALICK, AM
WANG, GH
WALLS, FC
机构：
[1] Univ of California, San Francisco,, CA, USA, Univ of California, San Francisco, CA, USA
来源：
ANALYTICAL CHEMISTRY | 1986年 / 58卷 / 07期
关键词：
MASS SPECTROMETERS - Equipment;
D O I：
10.1021/ac00298a009
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A new liquid secondary ionization mass spectrometry (LSIMS) ion source employing a Cs** plus primary beam has been constructed, and its performance has been compared against a standard Kratos MS-50 fast atom bombardment (FAB) source using Xe atoms. The LSIMS source has improved high-voltage feedthroughs (20 kV), a mechanical Cs** plus gun position adjuster, and more efficient secondary ion collection optics. The LSIMS source was found to give approximately a factor of 2 increase in maximum quasi-molecular ion (MH** plus or M plus Na** plus ) intensity when a 0. 1 mu A Cs** plus primary beam was used, and a factor of 5 with a 1. 0 mu A primary beam.
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页码：1308 / 1311
页数：4
相关论文
共 14 条
[1]   SECONDARY ION MASS-SPECTROMETRY WITH CESIUM ION PRIMARY BEAM AND LIQUID TARGET MATRIX FOR ANALYSIS OF BIOORGANIC COMPOUNDS [J].
ABERTH, W ;
STRAUB, KM ;
BURLINGAME, AL .
ANALYTICAL CHEMISTRY, 1982, 54 (12) :2029-2034
[2]   COMPARISON OF 3 GEOMETRIES FOR A CESIUM PRIMARY BEAM LIQUID SECONDARY ION MASS-SPECTROMETRY SOURCE [J].
ABERTH, W ;
BURLINGAME, AL .
ANALYTICAL CHEMISTRY, 1984, 56 (14) :2915-2918
[3]  
ABERTH W, 1983, ION FORMATION ORGANI, V25, P167
[4]   MASS-SPECTROMETRY OF LARGE, FRAGILE, AND INVOLATILE MOLECULES [J].
BUSCH, KL ;
COOKS, RG .
SCIENCE, 1982, 218 (4569) :247-254
[5]  
FALICK AM, UNPUB
[6]   COMPARISON OF CF-252 PLASMA DESORPTION AND FAST ATOM BOMBARDMENT MASS-SPECTROMETRY FOR ANALYSIS OF SMALL PEPTIDES [J].
FOHLMAN, J ;
PETERSON, PA ;
ROEPSTORFF, P ;
HOJRUP, P ;
KAMENSKY, I ;
SAWE, G ;
HAKANSSON, P ;
SUNDQUIST, B .
BIOMEDICAL MASS SPECTROMETRY, 1985, 12 (08) :380-387
[7]  
FORSBERG LS, 1982, J BIOL CHEM, V257, P3555
[8]   THE USE OF SURFACTANTS TO MODIFY MOLAR RESPONSE FACTORS IN THE SECONDARY ION MASS-SPECTROMETRY OF LIQUID SURFACES [J].
LIGON, WV ;
DORN, SB .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1984, 61 (01) :113-122
[9]   CHARACTERIZATION OF THE XENON ION FLUX PRODUCED BY A SADDLE-FIELD NEUTRAL-BEAM SOURCE [J].
LIGON, WV .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1982, 41 (03) :205-208
[10]   QUANTITATIVE BEHAVIOR OF SURFACTANTS AT THE LIQUID VACUUM INTERFACE BY SECONDARY ION MASS-SPECTROMETRY [J].
LIGON, WV ;
DORN, SB .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1984, 57 (01) :75-90
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