NEW INSIGHT INTO THE CATALYTIC MECHANISM OF CHORISMATE MUTASES FROM STRUCTURAL STUDIES

被引：110
|
作者：
LEE, AY
STEWART, JD
CLARDY, J
GANEM, B
机构：
来源：
CHEMISTRY & BIOLOGY | 1995年 / 2卷 / 04期
关键词：
D O I：
10.1016/1074-5521(95)90269-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chorismate mutase catalyzes the rearrangement of chorismic acid to prephenic acid, which is the first committed step in the biosynthesis of aromatic amino acids. Its catalytic mechanism has been much studied, but is poorly understood. Recent structural information on enzymes from two species, and on an antibody that catalyzes the same reaction, has shed new light on this topic.
引用
收藏
页码：195 / 203
页数：9
相关论文
共 50 条
  • [1] On the mechanism of chorismate mutases: Revisiting structural requirements for catalysis
    Galopin, CC
    Ganem, B
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (22) : 2885 - 2886
  • [2] New structural and chemical insight into the catalytic mechanism of epoxide hydrolases
    Armstrong, RN
    Cassidy, CS
    DRUG METABOLISM REVIEWS, 2000, 32 (3-4) : 327 - 338
  • [3] Evolution of allosteric regulation in chorismate mutases from early plants
    Kroll, Kourtney
    Holland, Cynthia K.
    Starks, Courtney M.
    Jez, Joseph M.
    BIOCHEMICAL JOURNAL, 2017, 474 : 3705 - 3717
  • [4] Structural and mechanistic insight into the mechanism of flavin activation in eukaryotic UDP-galactopyranose mutases
    Sobrado, Pablo
    Briggs, Michelle
    Dhatwalia, Richa
    Singh, Harkewal
    Tanner, John J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [5] Structural Evolution of Differential Amino Acid Effector Regulation in Plant Chorismate Mutases
    Westfall, Corey S.
    Xu, Ang
    Jez, Joseph M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (41) : 28619 - 28628
  • [6] New Insight into the Catalytic Mechanism of Bacterial MraY from Enzyme Kinetics and Docking Studies
    Liu, Yao
    Rodrigues, Joao P. G. L. M.
    Bonvin, Alexandre M. J. J.
    Zaal, Esther A.
    Berkers, Celia R.
    Heger, Michal
    Gawarecka, Katarzyna
    Swiezewska, Ewa
    Breukink, Eefjan
    Egmond, Maarten R.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (29) : 15057 - 15068
  • [7] Properties and Functional Analysis of Two Chorismate Mutases from Maritime Pine
    de la Torre, Fernando
    Medina-Morales, Beatriz
    Blanca-Reyes, Irene
    Pascual, M. Belen
    Avila, Concepcion
    Canovas, Francisco M.
    Castro-Rodriguez, Vanessa
    CELLS, 2024, 13 (11)
  • [8] Structural insight into catalytic mechanism of PET hydrolase
    Xu Han
    Weidong Liu
    Jian-Wen Huang
    Jiantao Ma
    Yingying Zheng
    Tzu-Ping Ko
    Limin Xu
    Ya-Shan Cheng
    Chun-Chi Chen
    Rey-Ting Guo
    Nature Communications, 8
  • [9] Structural insight into catalytic mechanism of PET hydrolase
    Han, Xu
    Liu, Weidong
    Huang, Jian-Wen
    Ma, Jiantao
    Zheng, Yingying
    Ko, Tzu-Ping
    Xu, Limin
    Cheng, Ya-Shan
    Chen, Chun-Chi
    Guo, Rey-Ting
    NATURE COMMUNICATIONS, 2017, 8
  • [10] On the mechanism of chorismate mutases: Clues from wild-type E-coli enzyme and a site-directed mutant related to yeast chorismate mutase
    Galopin, CC
    Zhang, S
    Wilson, DB
    Ganem, B
    TETRAHEDRON LETTERS, 1996, 37 (48) : 8675 - 8678
12345