CONFIRMATIONAL ANALYSIS OF BETA-AGONISTS BY CRYOTRAPPING GAS-CHROMATOGRAPHY FOURIER-TRANSFORM INFRARED SPECTROMETRY

被引：8
|
作者：
VISSER, T [1 ]
VREDENBREGT, MJ [1 ]
DEJONG, APJM [1 ]
VANROSSUM, HJ [1 ]
STEPHANY, RW [1 ]
VANGINKEL, LA [1 ]
机构：
[1] NATL INST PUBL HLTH & ENVIRONM PROTECT,RESIDUE ANAL LAB,3720 BA BILTHOVEN,NETHERLANDS
来源：
ANALYST | 1994年 / 119卷 / 12期
关键词：
GAS CHROMATOGRAPHY; INFRARED SPECTROMETRY; BETA-AGONISTS; MABUTEROL; MAPENTEROL; SALBUTAMOL; CIMATEROL; CLENBUTEROL; CIMBUTEROL; BROMOBUTEROL;
D O I：
10.1039/an9941902681
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Cryotrapping gas chromatography-Fourier transform infrared spectrometry has been used for confirmation analysis of the beta-agonists clenbuterol, salbutamol, mabuterol, bromobuterol, cimaterol, cimbuterol and mapenterol in urine and liver samples of veal calves, subsequent to selected ion detection gas chromatography-mass spectrometry. Samples have been analysed as their trimethylsilyl and methylboronate derivatives. Methylboronate derivatives yielded strongly diminished chemical background and interference levels in the infrared chromatograms of standards and samples. The limit of identification for methylboronate derivatives was at the low ppb level in incurred samples. The similarity of analyte and reference spectra, together with the retention time, was found to be a useful criterion for confirmation of unknown compounds.
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页码：2681 / 2685
页数：5
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