Organic components from scallop shell increase expression of keratinocyte growth factor in human skin fibroblast

被引:0
|
作者
Akane Torita
Akimi Miyamoto
Kohsuke Ishiguro
Sachie Yamamoto
Yasushi Hasegawa
机构
[1] Muroran Institute of Technology,College of Environmental Technology
来源
Fisheries Science | 2011年 / 77卷
关键词
Effective utilization; KGF; Scallop shell; Skin fibroblasts; Skin keratinocytes;
D O I
暂无
中图分类号
学科分类号
摘要
We observed previously that scallop shells contain organic components that have various useful applications for skin. The organic components from scallop shell (scallop shell extract) enhance the turnover rate of the rat skin epidermal layer and increase the rate of recovery of UVB-induced injury to rat dorsal skin. We investigated the effect of scallop shell extract on the expression of keratinocyte growth factor (KGF) from human skin fibroblasts because it has been reported that KGF promotes wound healing and reduces the generation of UVB-induced free radicals in skin. Scallop shell extract increased the mRNA expression level of KGF in skin fibroblasts and the secretion of KGF from the fibroblasts at the protein level. These results suggest that the scallop shell extract may promote recovery from UVB-induced injury in skin through an increase in the secretion of KGF from the fibroblast cell.
引用
收藏
页码:263 / 269
页数:6
相关论文
共 50 条
  • [1] Organic components from scallop shell increase expression of keratinocyte growth factor in human skin fibroblast
    Torita, Akane
    Miyamoto, Akimi
    Ishiguro, Kohsuke
    Yamamoto, Sachie
    Hasegawa, Yasushi
    FISHERIES SCIENCE, 2011, 77 (02) : 263 - 269
  • [2] Regulation of keratinocyte growth factor gene expression in human skin fibroblasts
    Tang, AM
    Gilchrest, BA
    JOURNAL OF DERMATOLOGICAL SCIENCE, 1996, 11 (01) : 41 - 50
  • [3] Immunohistochemical analysis of keratinocyte growth factor and fibroblast growth factor 10 expression in psoriasis
    Kovacs, D
    Falchi, M
    Cardinali, G
    Raffa, S
    Carducci, M
    Cota, C
    Amantea, A
    Torrisi, MR
    Picardo, M
    EXPERIMENTAL DERMATOLOGY, 2005, 14 (02) : 130 - 137
  • [4] Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression
    Sun, Ding-Ping
    Yeh, Ching-Hua
    So, Edmund
    Wang, Li-Yun
    Wei, Tsui-Shan
    Chang, Ming-Shi
    Hsing, Chung-Hsi
    CYTOKINE, 2013, 62 (03) : 360 - 368
  • [5] Differential gene expression of human keratinocyte HaCaT cells induced by fibroblast growth factor 10 treatment
    Xia Chen
    Jianzhong Li
    Wei Hu
    Shengli Yang
    Yi Gong
    Molecular and Cellular Biochemistry, 2010, 342 : 71 - 85
  • [6] Differential gene expression of human keratinocyte HaCaT cells induced by fibroblast growth factor 10 treatment
    Chen, Xia
    Li, Jianzhong
    Hu, Wei
    Yang, Shengli
    Gong, Yi
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2010, 342 (1-2) : 71 - 85
  • [7] Effects of fibroblast growth factor 8, fibroblast growth factor 9 and keratinocyte growth factor on multiplication and locomotion in human teratocarcinoma cells in vitro
    Granerus, M
    Engström, W
    ANTICANCER RESEARCH, 2003, 23 (2B) : 1313 - 1316
  • [8] Basic fibroblast growth factor and keratinocyte growth factor over-expression in benign prostatic hyperplasia
    Boget, S
    Leriche, A
    Revol, A
    FARMACO, 2001, 56 (5-7): : 467 - 469
  • [9] Keratinocyte growth factor can increase the expression of the EDA plus fibronectin
    Vas, K.
    Koermoes, B.
    Bebes, A.
    Goblos, A.
    Szell, M.
    Kemeny, L.
    Bata-Csoergoe, Z.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S27 - S27
  • [10] Ontogeny of expression of basic fibroblast growth factor and its receptors in human fetal skin
    陈伟
    付小兵
    葛世丽
    孙同柱
    盛志勇
    中华创伤杂志(英文版), 2005, (06) : 332 - 338