Pharmacology of Itraconazole

被引:0
|
作者
Karel De Beule
Jef Van Gestel
机构
[1] Janssen Research Foundation,
[2] Janssen-Cilag,undefined
来源
Drugs | 2001年 / 61卷
关键词
Adis International Limited; Cyclodextrin; Itraconazole; Antimicrob Agent; Oral Solution;
D O I
暂无
中图分类号
学科分类号
摘要
Itraconazole is a triazole antifungal agent that has a broad spectrum of activity and is well tolerated. Itraconazole is highly efficacious, particularly because its main metabolite, hydroxy-itraconazole, also has considerable antifungal activity.
引用
收藏
页码:27 / 37
页数:10
相关论文
共 50 条
  • [1] Pharmacology of itraconazole
    De Beule, K
    Van Gestel, J
    DRUGS, 2001, 61 (Suppl 1) : 27 - 37
  • [2] Pharmacokinetics and pharmacology of terbinafine and itraconazole
    Leyden, J
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1998, 38 (05) : S42 - S47
  • [3] Clinical pharmacology of itraconazole in children and adolescents
    Drogouti E.
    Pana Z.D.
    Tragiannidis A.
    Hempel G.
    Groll A.
    Current Fungal Infection Reports, 2015, 9 (2) : 65 - 73
  • [5] Itraconazole: an update on pharmacology and clinical use for treatment of invasive and allergic fungal infections
    Lestner, Jodi
    Hope, William W.
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2013, 9 (07) : 911 - 926
  • [6] Itraconazole induces cardiac dysfunction-Translation of safety pharmacology data to humans
    Derakhchan, Kathy
    Qu, Yusheng
    Sutherland, Weston
    Fang, Mei
    Gao, Baoxi
    Chui, Ray W.
    Vargas, Hugo M.
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2013, 68 (01) : E12 - E12
  • [7] Bioanalytical methods for the determination of itraconazole and hydroxyitraconazole: overview from clinical pharmacology, pharmacokinetic, pharmacodynamic and metabolism perspectives
    Yao, Ming
    Srinivas, Nuggehally R.
    BIOMEDICAL CHROMATOGRAPHY, 2009, 23 (07) : 677 - 691
  • [8] Itraconazole
    Rogers, T.
    MYCOSES, 2017, 60 : 50 - 50
  • [9] Itraconazole
    Keller, Krista A.
    JOURNAL OF EXOTIC PET MEDICINE, 2011, 20 (02) : 156 - 160
  • [10] Itraconazole
    Martin, S
    COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN, 1999, 21 (02): : 145 - 147