An artificial intelligence tool for bioprocess monitoring: application to continuous production of gluconic acid by immobilized Aspergillus niger

被引:0
|
作者
N.V. Sankpal
J.J.S. Cheema
S.S. Tambe
B.D. Kulkarni
机构
[1] Chemical Engineering Division,
[2] National Chemical Laboratory,undefined
来源
Biotechnology Letters | 2001年 / 23卷
关键词
artificial intelligence; continuous fermentation; gluconic acid; immobilization; monitoring; symbolic regression;
D O I
暂无
中图分类号
学科分类号
摘要
Experimental data on continuous fermentation of sucrose and glucose solution at low pH to gluconic acid by Asprgillus niger immobilized on cellulose fabric show complex dynamic behaviour including a decline in yield. The data have been analyzed using an artificial intelligence based symbolic regression technique to provide a mathematical model for predicting values of conversion 5, 10 and 15 h ahead values of conversion. These predictions can be used during continuous operations to monitor the bioprocess and adjust the residence time of fermentation to get complete and more efficient conversion of sucrose or glucose to gluconic acid.
引用
收藏
页码:911 / 916
页数:5
相关论文
共 50 条
  • [1] An artificial intelligence tool for bioprocess monitoring:: application to continuous production of gluconic acid by immobilized Aspergillus niger
    Sankpal, NV
    Cheema, JJS
    Tambe, SS
    Kulkarni, BD
    BIOTECHNOLOGY LETTERS, 2001, 23 (11) : 911 - 916
  • [2] Continuous production of gluconic acid by Aspergillus niger immobilized on a cellulosic support:: study of low pH fermentative behaviour of Aspergillus niger
    Sankpal, NV
    Joshi, AP
    Sutar, II
    Kulkarni, BD
    PROCESS BIOCHEMISTRY, 1999, 35 (3-4) : 317 - 325
  • [3] Production of gluconic acid from whey by free and immobilized Aspergillus niger
    Mukhopadhyay, R
    Chatterjee, S
    Chatterjee, BP
    Banerjee, PC
    Guha, AK
    INTERNATIONAL DAIRY JOURNAL, 2005, 15 (03) : 299 - 303
  • [4] PRODUCTION OF GLUCONIC ACID BY ASPERGILLUS-NIGER IMMOBILIZED ON POLYURETHANE FOAM
    VASSILEV, NB
    VASSILEVA, MC
    SPASSOVA, DI
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1993, 39 (03) : 285 - 288
  • [5] A kinetic model for gluconic acid production by Aspergillus niger
    Znad, H
    Blazej, M
    Báles, V
    Markos, J
    CHEMICAL PAPERS, 2004, 58 (01) : 23 - 28
  • [6] GLUCONIC ACID PRODUCTION AT HIGH-CONCENTRATIONS BY ASPERGILLUS-NIGER IMMOBILIZED ON A NONWOVEN FABRIC
    SAKURAI, H
    LEE, HW
    SATO, S
    MUKATAKA, S
    TAKAHASHI, J
    JOURNAL OF FERMENTATION AND BIOENGINEERING, 1989, 67 (06): : 404 - 408
  • [7] Optimization of fermentation conditions for gluconic acid production using Aspergillus niger immobilized on cellulose microfibrils
    Sankpal, NV
    Kulkarni, BD
    PROCESS BIOCHEMISTRY, 2002, 37 (12) : 1343 - 1350
  • [8] Production of gluconic acid by immobilized in pumice stones mycelium of Aspergillus niger using unconventional oxygenation of culture
    Fiedurek, J
    BIOTECHNOLOGY LETTERS, 2001, 23 (21) : 1789 - 1792
  • [9] Production of gluconic acid by immobilized in pumice stones mycelium of Aspergillus niger using unconventional oxygenation of culture
    Jan Fiedurek
    Biotechnology Letters, 2001, 23 : 1789 - 1792
  • [10] Production of gluconic acid by free and immobilized cells of recombinant Aspergillus niger in batch and repeated batch cultures
    El-Enshasy, HA
    DEUTSCHE LEBENSMITTEL-RUNDSCHAU, 2003, 99 (10) : 409 - 415