Lipid biology of the podocyte—new perspectives offer new opportunities

被引：0
|
作者：
Alessia Fornoni
Sandra Merscher
Jeffrey B. Kopp
机构：
[1] Peggy and Harold Katz Family Drug Discovery Center,Division of Nephrology and Hypertension
[2] University of Miami Miller School of Medicine,undefined
[3] Kidney Disease Section,undefined
[4] Kidney Diseases Branch,undefined
[5] National Institute of Diabetes and Digestive and Kidney Diseases,undefined
[6] NIH,undefined
来源：
Nature Reviews Nephrology | 2014年 / 10卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Lipids and lipid-related enzymes might modulate podocyte functionLipid biology is important in understanding the pathogenesis of glomerular diseases of metabolic and nonmetabolic originPlasma membrane and intracellular lipids can modulate podocyte function irrespective of circulating lipidsTherapeutic strategies that target cellular lipids, such as cholesterol and sphingolipids, might be protective in kidney disease
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页码：379 / 388
页数：9
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