Severe respiratory symptoms to oxaliplatin infusion: a case report of delayed hypersensitivity reaction

被引：0
|
作者：
Simona Potenza
Guglielmo Nasti
Ottaiano Alessandro
Amelia Filippelli
Francesco Rossi
Annalisa Capuano
机构：
[1] Second University of Naples,Department of Experimental Medicine, Section of Pharmacology “L. Donatelli”
[2] ‘G. Pascale’ Foundation,National Cancer Institute of Naples, Colorectal Department
来源：
Investigational New Drugs | 2010年 / 28卷
关键词：
Colorectal cancer; Chemotherapy; Oxaliplatin; Hypersensitivity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A 46-year-old man with adenocarcinoma of the sigmoid colon developed a hypersensitivity reaction after the sixth cycle of combination chemotherapy with oxaliplatin infusion. Hypersensitivity to oxaliplatin occurring, after several courses of therapy, in about 10–15% of patients, especially during or immediately after the oxaliplatin infusion. In this case report we present a delayed hypersensitivity reaction, consisting in dysesthesia and laryngeal spasm developed 10 h after the sixth administration of oxaliplatin.
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页码：185 / 186
页数：1
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