Advances in the diagnosis, pathogenesis and treatment of CIDP

Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common chronic autoimmune neuropathy. In this Review, Marinos Dalakas provides an update on the diagnosis of this disease, including recently devised consensus criteria. CIDP treatments—primarily corticosteroids, intravenous immunoglobulin and plasmapheresis—and ongoing challenges in trial design are discussed, together with potential therapeutic approaches that are emerging from advances in our understanding of the underlying immunopathology of this disease.