Design, synthesis and characterization of 1 H-pyridin-4-yl-3, 5-disubstituted indazoles and their anti-inflammatory and analgesic activity

被引:0
|
作者
ARAVA VEERA REDDY
SURENDRAREDDY GOGIREDDY
P K DUBEY
MADHAVA REDDY B
VEERESH B
机构
[1] R&D Centre,Department of Chemistry
[2] Suven Life Sciences Ltd.,Department of Pharmacology & Toxicology
[3] J.N.T. University,undefined
[4] G. Pulla Reddy College of Pharmacy,undefined
来源
关键词
1; -pyridin-4-yl-3; 5-disubstituted indazoles; anti-inflammatory and analgesic activity.;
D O I
暂无
中图分类号
学科分类号
摘要
A new series of 1H-pyridin-4-yl-indazole-3-carboxylic acid and its derivatives were synthesized from indazole-3-carboxylic acid methyl ester and 2-cyano-4-chloropyridine. All the new compounds have been characterized by spectral data and subsequently evaluated for their anti-inflammatory and analgesic activity.
引用
收藏
页码:433 / 438
页数:5
相关论文
共 50 条
  • [1] Design, synthesis and characterization of 1 H-pyridin-4-yl-3, 5-disubstituted indazoles and their anti-inflammatory and analgesic activity
    Reddy, Arava Veera
    Gogireddy, Surendrareddy
    Dubey, P. K.
    Reddy, Madhava B.
    Veeresh, B.
    JOURNAL OF CHEMICAL SCIENCES, 2015, 127 (03) : 433 - 438
  • [2] Design, synthesis and characterization of 1H-pyridin-4-yl-3,5-disubstituted indazoles and their AKT inhibition activity
    Gogireddy, Surendrareddy
    Kalle, Arunasree M.
    Dubey, P. K.
    Reddy, Arava Veera
    JOURNAL OF CHEMICAL SCIENCES, 2014, 126 (04) : 1055 - 1062
  • [3] Design, synthesis and characterization of 1H-pyridin-4-yl-3,5- disubstituted indazoles and their AKT inhibition activity
    SURENDRAREDDY GOGIREDDY
    ARUNASREE M KALLE
    P K DUBEY
    ARAVA VEERA REDDY
    Journal of Chemical Sciences, 2014, 126 : 1055 - 1062
  • [4] NON-STEROIDAL ANTI-INFLAMMATORY AGENTS .2. SYNTHESIS OF 4',5-DISUBSTITUTED 3-BIPHENYLYLACETIC ACIDS AND THEIR DERIVATIVES WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES
    TAMURA, Y
    YOSHIMOTO, Y
    KUNIMOTO, K
    TADA, S
    MATSUMURA, S
    MURAYAMA, M
    SHIBATA, Y
    ENOMOTO, H
    JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (01) : 43 - 47
  • [5] 1,5-disubstituted indazol-3-ols with anti-inflammatory activity
    Schindler, R
    Fleischhauer, I
    Hofgen, N
    Sauer, W
    Egerland, U
    Poppe, H
    Heer, S
    Szelenyi, I
    Kutscher, B
    Engel, J
    ARCHIV DER PHARMAZIE, 1998, 331 (01) : 13 - 21
  • [6] Analgesic and anti-inflammatory activity of quinoxaline derivatives: Design synthesis and characterization
    Meka, Geethavani
    Chintakunta, Ramakrishna
    RESULTS IN CHEMISTRY, 2023, 5
  • [7] Synthesis and Characterization of 2, 5-Disubstituted-1, 3, 4-oxadiazoles as Potential Anti-inflammatory Agents;
    Ilango, K
    Valentina, P.
    Umarani, N.
    Kumar, T.
    JOURNAL OF YOUNG PHARMACISTS, 2009, 1 (01) : 72 - 76
  • [8] NONSTEROID ANTI-INFLAMMATORY AGENTS .3. SYNTHESIS AND ANALGESIC-ANTI-INFLAMMATORY ACTIVITY OF 4-(PYRROL-1-YL)PHENYLACETAMIDES AND 4-(PYRROL-1-YL)PHENETHYLAMINES
    STEFANCICH, G
    ARTICO, M
    CORELLI, F
    MASSA, S
    PANTALEONI, GC
    PALUMBO, G
    FANINI, D
    GIORGI, G
    FARMACO-EDIZIONE SCIENTIFICA, 1984, 39 (09): : 752 - 764
  • [9] SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF NEW (5 (SUBSTITUTED PHENYL)-2,3-DIHYDRO-3-PHENYLPYRAZOL-1-YL) (PYRIDIN-3-YL) METHANONE DERIVATIVES
    Tabassum, Ruby
    Mohammad, Noor
    Kumari, Poonam
    Bharatia, Rakesh
    Srivastava, Neha
    Yogi, Bhumika
    Sinha, Anshuman
    Gupta, Sujeet K.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 27 (01) : 107 - 112
  • [10] Synthesis and Analgesic and Anti-inflammatory Activity of 4-(2-Aryl-3-aroyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic Acids
    V. L. Gein
    D. V. Chalkov
    A. V. Romanova
    O. V. Bobrovskaya
    S. V. Chashchina
    M. V. Dmitriev
    Russian Journal of Organic Chemistry, 2025, 61 (1) : 16 - 25